ANTI-C-MYC (PTHR58, SER62) RABBIT PAB Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

The transcription factor c-Myc is a short-lived nuclear phosphoprotein involved in cell proliferation, differentiation, and cancer. Expression of c-Myc is strictly controlled by mitogens and is required for cell cycle entry. c-Myc binds to DNA and activates transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro at Ser⁶² by MAP Kinase, and in vivo at both Thr⁵⁸ and Ser⁶² although the pathways and kinases acting in vivo have not been identified. Mutation of Thr⁵⁸ and Ser⁶² to Ala inhibits the ability of c-Myc to stimulate transcription. c-Myc, a ~45 kDa protein that migrates with an apparent molecular weight of ~64-67kDa in reducing SDS-PAGE, appears to regulate multiple aspects of growth control; c-Myc promotes cell proliferation in the presence of Cdk inhibitors and induces apoptosis upon overexpression in serum deprived cells.

ANTI-C-MYC (PTHR58, SER62) RABBIT PAB Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-C-MYC (PTHR58, SER62) RABBIT PAB Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Riedel-de Haen AG	--		United States	6773	87
SIGMA-RBI	--		Switzerland	6896	91
EMD Biosciences, Inc.	--	technical@calbiochem.com	United States	6529	66
VWR International	--	solutions@vwr.com	United Kingdom	6548	82

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• ANTI-PHOSPHO-C-MYC (PHOSPHOTHREONINE 58/PHOSPHOSERINE 62)
• ANTI-C-MYC, PHOSPHO-SPECIFIC (THR58, SER62), HUMAN
• ANTI-C-MYC (PTHR58, SER62) RABBIT PAB
• PHOSPHO-C-MYC (AB-1) POLYCLONAL ANTIBODY
• Anti-phospho-c-Myc (pThr58/pSer62) antibody produced in rabbit
• Antibodies for Cell Cycle
• Cell Biology
• M
• Other
• Antibodies to Nuclear ProteinsAlphabetical Index