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ABT-492

ABT-492 Struktur
189279-58-1
CAS-Nr.
189279-58-1
Englisch Name:
ABT-492
Synonyma:
Delafloxacin;Delafloxacine;Delafloxacin Impurity;WQ3034;CS-711;ABT-492;RX-3341;CS-2335;Delafloxacinum;ABT492/ABT-492
CBNumber:
CB12561456
Summenformel:
C18H12ClF3N4O4
Molgewicht:
440.76
MOL-Datei:
189279-58-1.mol

ABT-492 Eigenschaften

Schmelzpunkt:
238-241℃
Siedepunkt:
698.5±55.0 °C(Predicted)
Dichte
1.796
storage temp. 
2-8°C
L?slichkeit
DMSO (Slightly), Methanol (Very Slightly, Heated, Sonicated)
pka
5.49±0.50(Predicted)
Aggregatzustand
powder
Farbe
white to beige
CAS Datenbank
189279-58-1

Sicherheit

ABT-492 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Delafloxacin is a potent agent and broad-spectrum anionic fluoroquinolone against Streptococcus pneumoniae and diverse group of pathogens.

Biochem/physiol Actions

Delafloxacin is a fluoroquinolone antibiotic active against both Gram-negative and Gram-positive bacteria such as MRSA. Delafloxacin targets both DNA gyrase and topoisomerase IV, inhibiting DNA synthesis. Unlike most fluoroquinolones, delafloxacin is weakly acidic, which increases its potency in an acidic environments such as those existing in inflammatory cells and in skin and soft tissue infections. Delafloxacin shows good activity against most fluoroquinolone-resistant strains.

ABT-492 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Benzenepropanoic acid, α-(ethoxymethylene)-2,4,5-trifluoro-β-oxo-, ethyl ester 3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester 1-(6-Amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 3-Quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-[3-(2-methyl-1-oxopropoxy)-1-azetidinyl]-4-oxo-, ethyl ester Ethyl 2,4,5-trifluorobenzoylacetate 2,4,5-Trifluorobenzoic acid 3-quinolinecarboxylic acid, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester 2,4,5-Trifluorobenzoyl chloride ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE 3-Hydroxyazetidine hydrochloride 1-Methylpyrrolidin

Downstream Produkte

Delafloxacin meglumine

ABT-492 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 164)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328
 sales03@chemcn.cn China 970 58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. 		+86-18600796368 +86-18600796368
 sales@sjar-tech.com China 484 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21634 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32956 60
Klong Industrial Co., Ltd 		0086-519-68231162
info@klongchem.com CHINA 131 58
Jinan Shengqi pharmaceutical Co,Ltd 		86+18663751872
christine@shengqipharm.com CHINA 491 58
HubeiwidelychemicaltechnologyCo.,Ltd 		18627774460
faith@widelychemical.com CHINA 742 58
Standardpharm Co. Ltd. 		86-714-3992388
overseasales1@yongstandards.com United States 14332 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29810 58

189279-58-1()Verwandte Suche:

  • ABT-492
  • 1-(6-Amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylic acid
  • Delafloxacinum
  • 3-Quinolinecarboxylic acid, 1-(6-aMino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-
  • WQ3034
  • ABT-492(WQ-3034)
  • ABT492/ABT-492
  • 1-(6-aMino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • RX-3341
  • ABT-492/Delafloxacin
  • Delafloxacin, ABT-492
  • 3-(6-Amino-3,5-difluoro-pyridin-2-ylamino)-2-{2,5-difluoro-4-[3-(3-methyl-2-oxo-butyl)-cyclobutyl]-benzoyl}-acrylic acid ethyl ester
  • DELAFLOXACIN;RX-3341;WQ-3034;ABT492
  • 1-(6-Amino-3,5-difluoro-pyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-quinolin-3-carboxylic acid
  • Delafloxacin Free Acid
  • DELAFLOXACIN;DELAFLOXACINUM;RX-3341;WQ-3034;ABT492;ABT 492
  • CS-2335
  • DELAFLOXACINUM; RX-3341; WQ-3034; ABT492; ABT 492; ABT-492;WQ3034;WQ 3034
  • CS-711
  • 1-(6-Amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-...
  • Delafloxacin impurities7
  • Delafloxacin
  • Delafloxacin Impurity
  • Delafloxacine
  • 2H5]-Delafloxacin
  • Delafloxacin API
  • 3-?Quinolinecarboxylic acid, 1-?(6-?amino-?3,?5-?difluoro-?2-?pyridinyl)?-?6-?fluoro-?1,?4-?dihydro-?7-?[3-?(2-?methyl-?1-?oxopropoxy)&
  • 189279-58-1
  • C18H12ClF3N4O4
  • API
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