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Arecolinhydrobromid

Arecoline hydrobromide  Struktur
300-08-3
CAS-Nr.
300-08-3
Bezeichnung:
Arecolinhydrobromid
Englisch Name:
Arecoline hydrobromide
Synonyma:
ArecoL;arecane;Taeniolin;ARECOLINE HBR;Arecoline hydr;arecolinebromide;ine hydrobromide;arekolinhydrobromid;ARECOLINIUM BROMIDE;Argatroban Anhydrous
CBNumber:
CB1250752
Summenformel:
C8H14BrNO2
Molgewicht:
236.11
MOL-Datei:
300-08-3.mol

Arecolinhydrobromid Eigenschaften

Schmelzpunkt:
171-175 °C
storage temp. 
Inert atmosphere,Room Temperature
L?slichkeit
H2O: 0.1 g/mL, clear, colorless
Aggregatzustand
Powder
pka
6.84(at 25℃)
Farbe
White to light yellow
Merck 
14,778
BRN 
3914826
Stabilit?t:
Stable for 2 years from date of purchase as supplied. Solutions are not stable – make fresh daily.
InChI
InChI=1S/C8H13NO2.BrH/c1-9-5-3-4-7(6-9)8(10)11-2;/h4H,3,5-6H2,1-2H3;1H
InChIKey
AXOJRQLKMVSHHZ-UHFFFAOYSA-N
SMILES
C1(C(=O)OC)=CCCN(C)C1.Br
CAS Datenbank
300-08-3(CAS DataBase Reference)
EPA chemische Informationen
Arecoline hydrobromide (300-08-3)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,T
R-S?tze: 22-23/24/25
S-S?tze: 45-38-36/37/39-28A
RIDADR  1544
WGK Germany  3
RTECS-Nr. QT2275000
8
HazardClass  6.1
PackingGroup  III
HS Code  29399990
Toxizit?t LD50 par-rat: 270 mg/kg ABMGAJ 28,681,72
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P312 BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Arecolinhydrobromid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S38:Bei unzureichender Belüftung Atemschutzger?t anlegen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

WHITE FINE POWDER

Verwenden

Arecoline is a muscarinic acetylcholine receptor agonist. Arecoline induces ADP ribosylation of histones and chromatid relaxation in spleen and bone marrow cells. In a study, a controlled trial involving 122 dogs experimentally infected with Echinococcus

Allgemeine Beschreibung

Arecoline is an alkaloid obtained from theseeds of the betel nut (Areca catechu). For many years, nativesof the East Indies have consumed the betel nut as asource of a euphoria-creating substance.

Sicherheitsprofil

Poison by parenteral,subcutaneous, and intravenous routes. When heated todecomposition it emits very toxic fumes of HBr and NOx.

Toxikologie

Eighty rats were randomly divided into four groups: a high-dose group (1000 mg/kg), a medium-dose group (200 mg/kg), a low-dose group (100mg/kg), and a blank control group. The doses were administered daily via gastric lavage for 14 consecutive days. There were no significant differences in the low-dose Arecoline hydrobromide (Ah) group compared to the control group (P>0.05) with regard to body weight, organ coefficients, hematological parameters, and histopathological changes. In this study, the rats in the high-dose group exhibited clear inhibitory effects on blood biochemical parameters, including ALT, TP, and BUN levels. It was demonstrated that the toxicity reaction was intensified at the higher dosage, and clinical dosing should occur within a safe dosage range. With a continuous increase in the Ah dose, organ damage was aggravated, with different degrees of congestion, degeneration, and necrosis observed. The results accurately reflected the liver and kidney changes, whereas the results for the changes in the lung were poor. Hence, a long-term, continuous high dose of Ah was toxic[4].

Arecolinhydrobromid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Arecolinhydrobromid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 462)Lieferanten
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Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
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Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+86-18791163155 +86-13119157289
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+86-13131129325
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+86-15271838296; +8615271838296
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airuikechemical co., ltd.
+undefined86-15315557071
sales02@sdzhonghuimaterial.com China 983 58

300-08-3(Arecolinhydrobromid)Verwandte Suche:


  • arecolinebromide
  • arekolinhydrobromid
  • arecane
  • ARECOLINE HYDROBROMIDE CHOLINERGIC AGONI ST
  • ARECOLIN HYDROBROMIDE VETRANAL, 250
  • ARECOLINE HYDROBROMIDE CRYSTALLINE
  • Arecoline hydrobromide, 99+%
  • 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide
  • ARECOLINE HYDROBROMIDE(P)
  • Argatroban Anhydrous
  • Arecoline HBr for research
  • Arecaidine methyl ester hydrobromide, Methyl 1-methyl-1,2,5,6-tetrahydronicotinate hydrobromide, Methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide, 1-Methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid methyl ester hydrobromide
  • Methyl 1-methyl-5,6-dihydro-2H-pyridine-3-carboxylate hydrobromide
  • Taeniolin
  • Arecoline hydrobromide ,98%
  • Areciline Hydrochloride,(S)
  • Methyl 1,2,5,6-tetrahydro-1-methylnicotinate
  • Methyl 1-methyl-1,2,5,6-tetrahydronicotinate hydrobromide1-Methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid methyl ester
  • 1,2,5,6-Tetrahydro-1-Methyl-3-pyridinecarboxylic Acid Methyl Ester HydrobroMide
  • 1-Methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic Acid Methyl Ester HydrobroMide
  • Methylarecaidine HydrobroMide
  • methyl-1,2,5,6-tetrahydro-1-methyl
  • nicotinicacid,1,2,5,6-tetrahydro-1-methyl-,methylester,hydrobromide
  • n-methyltetrahydronicotinicacidmethylesterhydrobromide
  • 1-METHYL-1,2,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROBROMIDE
  • METHYL 1-METHYL-1,2,5,6-TETRAHYDRONICOTINATE HYDROBROMIDE
  • METHYL 1-METHYL-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLATE HYDROBROMIDE
  • METHYL 1,2,5,6-TETRAHYDRO-1-METHYL-3-PYRIDINECARBOXYLATE HYDROBROMIDE
  • METHYL 1,2,5,6-TETRAHYDRO-1-METHYLNICOTINATE HYDROBROMIDE
  • ARECOLINIUM BROMIDE
  • ARECAIDINE METHYL ESTER HYDROBROMIDE
  • ARECOLINE HBR
  • ARECOLINE HYDROBROMIDE
  • Arecoline hydrobromide, 3-(Methoxycarbonyl)-1-methyl-1,2,5,6-tetrahydropyridine hydrobromide
  • Arecoline hydr
  • 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylic acid methyl ester, hydrobromide (1:1)
  • ArecoL
  • ine hydrobromide
  • 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid methyl ester bromide
  • methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate,hydrobromide
  • Arecoline hydrobromid
  • 99% Arecoline hydrobromide
  • Arecoline hydrobromide USP/EP/BP
  • Arecoline hydrobromide CAS
  • Arecoline hydrobromide (Arecoline bromide)
  • Arecoline hydrobromide, for HPLC >98%
  • Propanoylchloride,8-ethoxy-
  • Arecoline HBr|||Arecoline bromide
  • 300-08-3
  • 73069-28-9
  • C8H14BrNO2
  • C8H13NO2BrH
  • C8H13NO2HBr
  • C8H13NO2xHBr
  • 23611
  • Pyridines
  • Heterocyclic Building Blocks
  • Pyridine Alkaloids
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