CUDC-101
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- CAS-Nr.
- 1012054-59-9
- Englisch Name:
- CUDC-101
- Synonyma:
- CURIS;CS-330;CUDC101;CUDC-101;CUDC-101, >=98%;CUDC101;CUDC 101;CUDC101; CUDC 101; CUDC-101.;7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide;7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide;7-[[4-[(3-Ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanaMide
- CBNumber:
- CB12500941
- Summenformel:
- C24H26N4O4
- Molgewicht:
- 434.49
- MOL-Datei:
- 1012054-59-9.mol
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CUDC-101 Eigenschaften
- Schmelzpunkt:
- 174-177℃
- Dichte
- 1.28
- storage temp.
- -20°C
- L?slichkeit
- DMSO: soluble
- pka
- 9.47±0.20(Predicted)
- Aggregatzustand
- solid
- Farbe
- White or off-white
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- InChIKey
- PLIVFNIUGLLCEK-UHFFFAOYSA-N
CUDC-101 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
CUDC-101 is a potent multi-acting HDAC (histone deacetylase), EGFR (epidermal growth factor receptor), and HER2 ( human epidermal growth factor receptor 2) inhibitor for the treatment of cancer.
Allgemeine Beschreibung
A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC50 values of 4.4, 2.4, and 15.7 nM, respectively.
Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.
CUDC-101 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
CUDC-101 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 131)Lieferanten
1012054-59-9()Verwandte Suche:
- CUDC101
- CUDC-101
- 7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide
- HeptanaMide, 7-[[4-[(3-ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxy-
- 7-[[4-[(3-Ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanaMide
- 7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide CUDC-101
- 7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide
- CUDC-101, >=98%
- CUDC101; CUDC 101; CUDC-101.
- CS-330
- CUDC101;CUDC 101
- CURIS
- 1012054-59-9
- Inhibitor
- Antineoplastic
- Inhibitors
