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OROTIDINE

OROTIDINE Struktur
314-50-1
CAS-Nr.
314-50-1
Englisch Name:
OROTIDINE
Synonyma:
OROTIDINE;Orotidine ,98%;6-Carboxyuridine;URIDIN-6-CARBOXYLIC ACID;URIDINE-6-CARBOXYLIC ACID;orotidine free acid approx. 90%;Orotidine (Uridine-6-carboxylic acid);1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid;4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-;4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-
CBNumber:
CB1164936
Summenformel:
C10H12N2O8
Molgewicht:
288.21
MOL-Datei:
314-50-1.mol

OROTIDINE Eigenschaften

Schmelzpunkt:
>400 °C
Dichte
1.847±0.06 g/cm3(Predicted)
storage temp. 
−20°C
L?slichkeit
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Aggregatzustand
Solid
pka
2.62±0.20(Predicted)
Farbe
White to Off-White

Sicherheit

WGK Germany  3
HS Code  29349990

OROTIDINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Orotidine is a metabolite of Orotic Acid (O691500); a compound used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.

Definition

ChEBI: A nucleoside formed by attaching orotic acid to a ribose ring via a beta1N(1)-glycosidic bond.

Enzyminhibitor

This water-soluble ribonucleoside (FWfree-acid = 288.21 g/mol; CAS 314-50- 1; lmax of 267 nm in 0.1 N HCl (e = 9570 cm–1M–1; another report lists 9800) and 265 nm in 0.1 N methanolic NaOH (e = 8960 cm–1M–1; another report lists 7800)), first observed in Neurospora crassa, is also foound in the urine of cancer patients treated with 6-azauridine, Orotidine is most likely formed from OMP, its 5’-monophosphate ester and the direct precursor of UMP. Orotidine is readily hydrolyzed in dilute mineral acids. Target(s): orotate phosphoribosyltransferase; orotidine-5’-phosphate decarboxylase.

OROTIDINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


OROTIDINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 49)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387
1057@dideu.com China 3959 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Finetech Industry Limited
+86-27-87465837 +8618971612321
info@finetechnology-ind.com China 9639 58
NewCan Biotech Limited
+86-0571-86912261 +8613735419629
sales@newcanbio.com China 9981 58
Henan Alfa Chemical Co., Ltd

China 11415 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 49978 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76

314-50-1()Verwandte Suche:


  • OROTIDINE
  • URIDINE-6-CARBOXYLIC ACID
  • URIDIN-6-CARBOXYLIC ACID
  • Orotidine (Uridine-6-carboxylic acid)
  • 1,2,3,6-Tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-4-pyrimidinecarboxylic acid
  • 6-Carboxyuridine
  • 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2,6-diketo-pyrimidine-4-carboxylic acid
  • Orotidine ,98%
  • orotidine free acid approx. 90%
  • 3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,6-dioxopyrimidine-4-carboxylic acid
  • 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-3-β-D-ribofuranosyl-
  • 4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-3-b-D-ribofuranosyl-
  • 3-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
  • 314-50-1
  • C10H13N2O11P
  • C10H12N2O8
  • Biochemicals and Reagents
  • BioChemical
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
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