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Azoles

Azoles Struktur
421581-70-6
CAS-Nr.
421581-70-6
Englisch Name:
Azoles
Synonyma:
Azoles;2-Acetyl-7-methylbenzofuran;1-(7-Bromobenzofuran-2-yl)ethanone;5-Ethyl-3-p-tolyl-1,2,4-oxadiazole;5-Methyl-3-p-tolyl-1,2,4-oxadiazole;5-Propyl-3-p-tolyl-1,2,4-oxadiazole;5-Methyl-3-(p-tolyl)-1,2,4-oxadiazole;5-Propyl-3-(p-tolyl)-1,2,4-oxadiazole;5-Cyclohexyl-3-p-tolyl-1,2,4-oxadiazole;5-tert-Butyl-3-p-tolyl-1,2,4-oxadiazole
CBNumber:
CB11326926
Summenformel:
C14H8FN3O3
Molgewicht:
285.23
MOL-Datei:
421581-70-6.mol

Azoles Eigenschaften

Siedepunkt:
446.8±55.0 °C(Predicted)
Dichte
1.389±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
-2.78±0.37(Predicted)
CAS Datenbank
421581-70-6

Sicherheit

Azoles Chemische Eigenschaften,Einsatz,Produktion Methoden

Pharmazeutische Anwendungen

A large group of synthetic agents, which includes drugs used in bacterial and parasitic infections (5-nitroimidazoles; benzimidazoles). Antifungal azoles have in common an imidazole or triazole ring with N-carbon substitution. The activity is essentially fungistatic, but some of the newer triazoles exert fungicidal effects at therapeutic concentrations. They are effective in the topical treatment of dermatophytoses and superficial forms of candidosis; several are suitable for systemic administration.
Several molecular mechanisms of resistance have been elucidated. These include overexpression of efflux pump genes, point mutations in the gene that encodes the target enzyme, lanosterol demethylase, and overexpression of this gene. Changes in other enzymes involved in ergosterol biosynthesis, such as sterol desaturase, may also contribute to azole resistance.

Azoles Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Azoles Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 21)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd
027-67849912
sales@chemwish.com CHINA 10821 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30239 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58
Energy Chemical 021-021-58432009 400-005-6266
sales8178@energy-chemical.com China 44688 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912
sales@chemwish.com China 35896 56
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66099280 17798518460
cfzhang@aikonchem.com China 19915 55
9ding chemical ( Shanghai) Limited 4009209199
sales@9dingchem.com China 18209 56
Wuhan Chemwish Technology Co., Ltd 027-67849912
sales@chemwish.com China 9148 60

  • Azoles
  • 2-(3-Bromophenyl)-5-(trichloromethyl)-1,3,4-oxadiazole
  • 2-(3-Bromophenyl)-5-trichloromethyl-1,3,4-oxadiazole
  • 1-(7-Bromobenzofuran-2-yl)ethanone
  • 2-Acetyl-7-methylbenzofuran
  • 3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole
  • 3-(4-Bromophenyl)-5-cyclohexyl-1,2,4-oxadiazole
  • 5-(2-Chlorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
  • 5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
  • 5-Cyclohexyl-3-(p-tolyl)-1,2,4-oxadiazole
  • 5-Cyclohexyl-3-p-tolyl-1,2,4-oxadiazole
  • 5-Ethyl-3-(4-nitrophenyl)-1,2,4-oxadiazole
  • 5-Ethyl-3-p-tolyl-1,2,4-oxadiazole
  • 5-Methyl-3-(p-tolyl)-1,2,4-oxadiazole
  • 5-Methyl-3-p-tolyl-1,2,4-oxadiazole
  • 5-Propyl-3-(p-tolyl)-1,2,4-oxadiazole
  • 5-Propyl-3-p-tolyl-1,2,4-oxadiazole
  • 5-tert-Butyl-3-p-tolyl-1,2,4-oxadiazole
  • 1,2,4-Oxadiazole, 5-(4-fluorophenyl)-3-(3-nitrophenyl)-
  • 421581-70-6
  • C9H6BrClN2O
  • C14H8FN3O3
  • C9H4BrCl3N2O
  • FluoroCompounds
  • NitroCompounds
  • Azoles
  • blocks
  • Bromides
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