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ZARDAVERINE

ZARDAVERINE Struktur
101975-10-4
CAS-Nr.
101975-10-4
Englisch Name:
ZARDAVERINE
Synonyma:
ZARDAVENINE;ZARDAVERINE;6-(4-(Difluoromethoxy)-3-methoxyphenyl)pyridazin-3(2H)-one;6-[4-(DIFLUOROMETHOXY)-3-METHOXYPHENYL]-3(2H)-PYRIDAZINONE;3-[4-(difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one;3-[4-(difluoromethoxy)-3-methoxy-phenyl]-1H-pyridazin-6-one;3(2H)-Pyridazinone, 6-[4-(difluoromethoxy)-3-methoxyphenyl]-
CBNumber:
CB1106730
Summenformel:
C12H10F2N2O3
Molgewicht:
268.22
MOL-Datei:
101975-10-4.mol

ZARDAVERINE Eigenschaften

Dichte
1.38±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
L?slichkeit
DMSO : 100 mg/mL (372.83 mM; Need ultrasonic)
Aggregatzustand
Off-white to yellow solid.
pka
10.89±0.40(Predicted)
Farbe
White to light yellow
CAS Datenbank
101975-10-4

Sicherheit

WGK Germany  3

ZARDAVERINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Zardaverine can selectively inhibit?phosphodiesterase III (PDE III) from human platelets and?phosphodiesterase IV (PDE IV) from human polymorphonuclear leucocytes (PMN).

Definition

ChEBI: A pyridazinone derivative in which pyridazin-3(2H)-one is substituted at C-6 with a 4-(difluoromethoxy)-3-methoxyphenyl group. It is a phosphodiesterase inhibitor, selective for PDE3 and 4.

Biologische Aktivit?t

Phosphodiesterase inhibitor, selective for PDE3 and 4 (IC 50 values are 0.5 and 0.8 μ M respectively). Also available as part of the Phosphodiesterase Inhibitor Tocriset™ .

ZARDAVERINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

4'-Hydroxy-3'-methoxyacetophenon Hydrazine hydrate Glyoxylic acid monohydrate AMMONIUM

Downstream Produkte

ZARDAVERINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 83)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32956 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Haoyuan Chemexpress Co., Ltd. 021-58950125
info@chemexpress.com China 7552 61
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4861 58
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
info@tsbiochem.com China 8065 58
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189
 mychess007@163.com China 1994 55

101975-10-4()Verwandte Suche:

  • 6-[4-(DIFLUOROMETHOXY)-3-METHOXYPHENYL]-3(2H)-PYRIDAZINONE
  • ZARDAVERINE
  • ZARDAVENINE
  • 3-[4-(difluoromethoxy)-3-methoxy-phenyl]-1H-pyridazin-6-one
  • 3-[4-(difluoromethoxy)-3-methoxyphenyl]-1H-pyridazin-6-one
  • 3(2H)-Pyridazinone, 6-[4-(difluoromethoxy)-3-methoxyphenyl]-
  • 6-(4-(Difluoromethoxy)-3-methoxyphenyl)pyridazin-3(2H)-one
  • 101975-10-4
  • C12H10F2N2O3
  • C12H10F2N3O3
  • Phosphodiesterase Inhibitors
  • G Proteins and Cyclic Nucleotides
  • Cyclic Nucleotide Metabolism
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Cyclic Nucleotide related
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