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Fungichromin

Fungichromin Struktur
6834-98-6
CAS-Nr.
6834-98-6
Bezeichnung:
Fungichromin
Englisch Name:
Fungichromin
Synonyma:
Lagosin;Cogomycin;Fungichromin;Lagosin【antibiotic】;(3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one;Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-, (3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-
CBNumber:
CB0904201
Summenformel:
C35H58O12
Molgewicht:
670.83
MOL-Datei:
6834-98-6.mol

Fungichromin Eigenschaften

Schmelzpunkt:
157-162° (dec)
alpha 
D20 -227.7° (c = 0.53 in DMF)
Siedepunkt:
914.0±65.0 °C(Predicted)
Dichte
1.196±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
solid
pka
12.77±0.70(Predicted)
Farbe
Light yellow to yellow

Sicherheit

Toxizit?t LD50 in mice (mg/kg): 1624 orally; 33.3 i.p. (Umezawa, Tanaka)

Fungichromin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Lagosin is a pentaene antifungal produced by Streptomyces, first isolated in 1958 by researchers at MIT in the USA. The discovery was soon followed by several independent isolations as lagosin and cogomyin. Initially these metabolites were thought to be isomeric, but Pandey and colleagues at NCI definitively demonstrated they were identical. Structurally, lagosin is 14-hydroxyfilipin III and the most polar member of the filipin family of fungicides. Lagosin exhibits broad spectrum antifungal and antitumor activity and, like filipin, acts via interaction with cell membrane sterols.

Fungichromin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Fungichromin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 24)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences 		16314854226; +16314854226
 inquiry@bocsci.com United States 19741 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Raw material medicin reagent co.,Ltd
sales@njromanme.com China 4529 58
Lynnchem 86-(0)29-85992781 17792393971
 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890
 info@novachemistry.com United Kingdom 4381 58
Shanghai Han-Xiang Chemical Co., Ltd. 15971444841
 amber@biochempartner.com China 3061 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
 sales@rrkchem.com China 57423 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58

6834-98-6(Fungichromin)Verwandte Suche:

  • Lagosin
  • Fungichromin
  • Cogomycin
  • Lagosin【antibiotic】
  • Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-, (3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-
  • (3R,4S,6S,8S,10R,12R,14R,15R,16R,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,15,16,27-nonahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one
  • 6834-98-6
  • C35H58O12
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