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(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE

(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Struktur
354811-10-2
CAS-Nr.
354811-10-2
Englisch Name:
(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE
Synonyma:
IKK2-IN-4;IKK-2 INHIBITOR VI;IKK2 Inhibitor VI,IKK-2 Inhibitor VI;(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE;5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide;2-(carbamoylamino)-5-phenylthiophene-3-carboxamide;2-[(AMinocarbonyl)aMino]-5-phenyl-3-thiophenecarboxaMide;3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-phenyl-;5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide|||IKK2 Inhibitor IV
CBNumber:
CB0789277
Summenformel:
C12H11N3O2S
Molgewicht:
261.3
MOL-Datei:
Mol file

(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Eigenschaften

Schmelzpunkt:
>210°C (dec.)
Siedepunkt:
445.6±45.0 °C(Predicted)
Dichte
1.426±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
L?slichkeit
DMSO, Methanol (Slightly)
pka
14.00±0.70(Predicted)
Aggregatzustand
Solid
Farbe
Light Beige to Light Brown

Sicherheit

(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses.

Verwenden

(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE is an inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC50 = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses.

(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 30)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
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Finetech Industry Limited
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
Finetech Industry Limited 027-87465837 19945049750
sales@finetechnology-ind.com China 9648 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
Shanghai Chaolan Chemical Technology Center 021-QQ:65489617 15618227136
Sales@ATKchemical.com China 7312 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57423 58

  • (5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE
  • IKK-2 INHIBITOR VI
  • 2-[(AMinocarbonyl)aMino]-5-phenyl-3-thiophenecarboxaMide
  • 2-(carbamoylamino)-5-phenylthiophene-3-carboxamide
  • 3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-phenyl-
  • 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide
  • IKK2 Inhibitor VI,IKK-2 Inhibitor VI
  • 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide|||IKK2 Inhibitor IV
  • IKK2-IN-4
  • 354811-10-2
  • Aromatics Compounds
  • Aromatics
  • Inhibitors
  • Sulfur & Selenium Compounds
  • An ureido-thiophenecarboxamide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of IKK-2 (IC50 = 13 nM).
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