天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

6',7'-DIHYDROXYBERGAMOTTIN

6',7'-DIHYDROXYBERGAMOTTIN Struktur
145414-76-2
CAS-Nr.
145414-76-2
Englisch Name:
6',7'-DIHYDROXYBERGAMOTTIN
Synonyma:
6',7'-DIHYDROXYBERGAMOTTIN;6,7-dihydroxybergaMottin(DHB);4-[[(2E)-6,7-Dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one;7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-
CBNumber:
CB0765541
Summenformel:
C21H24O6
Molgewicht:
372.41
MOL-Datei:
145414-76-2.mol

6',7'-DIHYDROXYBERGAMOTTIN Eigenschaften

Schmelzpunkt:
112-113 °C
Siedepunkt:
578.2±50.0 °C(Predicted)
Dichte
1.260
storage temp. 
2-8°C
L?slichkeit
ethanol: soluble
pka
14.65±0.29(Predicted)
Aggregatzustand
Solid
Farbe
white to off-white

Sicherheit

WGK Germany  3

6',7'-DIHYDROXYBERGAMOTTIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 μM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6β-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by cytochrome P450 enzymes of the CYP3A subfamily results in a substantial increase in plasma concentration of these agents. However, giving a patient grapefruit juice or just 6,7-DHB could be advantageous in cases where a drug is metabolized too quickly by CYP3A4.

Verwenden

A minor metabolite of Bergamottin. Metabolization of Bergamottin by cytochromes P 450 2B6 and 3A5.

Biochem/physiol Actions

CYP3A4 inhibitor.

6',7'-DIHYDROXYBERGAMOTTIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

6',7'-DIHYDROXYBERGAMOTTIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 50)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Zheyan Biotech Co., Ltd. 		18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29810 58
Wuhan Nutra Biotechnology Co.,Ltd 		+8617786394783
 nutrabiotech@outlook.com China 300 58
Wuhan Kemi-Works Chemical Co., Ltd. 		+86-2785736489 +8618171418573
 sales@kemiworks.com China 729 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
China DongFan Chemical Co.,LTD 86-0571-85151182
China 5691 66
Wuhan Kemi-Works Chemical Co., Ltd 027-85736489
info@kemiworks.net China 540 57
Wuhan HengHeDa Pharm Co., Ltd. 27-27-84888682 18086046872
 hhdpharm@hotmail.com China 103 55
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
  • 4-[[(2E)-6,7-Dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one
  • 6',7'-DIHYDROXYBERGAMOTTIN
  • 6,7-dihydroxybergaMottin(DHB)
  • 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octen-1-yl]oxy]-
  • 145414-76-2
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Drug and Xenobiotic Metabolism
  • Multi-Drug Resistance and Drug Metabolism
  • Substrates, Inducers, Inhibitors
Copyright 2019 ? ChemicalBook. All rights reserved