ANTI-H2AX (PSER139) RABBIT PAB Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit has been used in immunofluorescence and western blotting.

Allgemeine Beschreibung

H2AX comprises 2-25% of the total H2A complement in human cells, whereas in the budding yeast it constitutes virtually all of the H2A molecules. It has N-terminal and C-terminal region with a central globular domain. The C-terminal region has sites for modification including acetylation, biotinylation and phosphorylation.

Biochem/physiol Actions

H2AX is critical for facilitating the assembly of specific DNA-repair complexes on damaged DNA. Ataxia-telangiectasia-mutated (ATM) is the major kinase involved in the phosphorylation of H2AX in response to DNA double-strand breaks. H2AX knockout mice are radiation sensitive and show retarted growth. They also are immune deficient with mutant males are infertile..

ANTI-H2AX (PSER139) RABBIT PAB Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-H2AX (PSER139) RABBIT PAB Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80

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• ANTI-PHOSPHO-HISTONE H2AX [PSER139]
• ANTI-H2AX (PSER139) RABBIT PAB
• Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit
• Anti-H2AXS139p
• Alphabetical Index
• Antibodies for EpigeneticsAntibodies for Gene Regulation and Expression
• Antibodies for Gene Regulation and Expression
• Antibodies in Chromatin Remodeling
• Antibodies to Histone ModificationsCell Biology
• Antibodies to Transcription RegulatorsAntibodies
• Functional Profiling of Stem Cells
• H
• Stem Cell Biology