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VH 101, phenol

VH 101, phenol Struktur
2306193-99-5
CAS-Nr.
2306193-99-5
Englisch Name:
VH 101, phenol
Synonyma:
Phenolic VH101;VH 101, phenol;E3 ligase Ligand 19;VH032-cyclopropane-F;(2S,4R)-1-((S)-2-(1-fluorocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;Inhibitor,E3 ligase-recruiting Moiety,inhibit,VHL ligand3,Ligands for E3 Ligase,VH032 cyclopropane F,VH032cyclopropaneF,VHL ligand-3,VH-032-cyclopropane-F;(2S,4R)-1-((S)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-[(2S)-2-[(1-fluorocyclopropyl)formamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
CBNumber:
CB05965564
Summenformel:
C26H33FN4O5S
Molgewicht:
532.63
MOL-Datei:
2306193-99-5.mol

VH 101, phenol Eigenschaften

Siedepunkt:
841.7±65.0 °C(Predicted)
Dichte
1.38±0.1 g/cm3(Predicted)
L?slichkeit
Soluble in DMSO
pka
9.12±0.35(Predicted)
Aggregatzustand
Solid
Farbe
White to yellow

Sicherheit

VH 101, phenol Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

VH032-cyclopropane-F (VH 101, phenol) is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal hydroxyl group. Allows rapid conjugation with many linkers containing active leaving groups. A basic building block for development of a protein degrader library.

VH 101, phenol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

VH 101, phenol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • E3 ligase Ligand 19
  • VH032-cyclopropane-F
  • VH 101, phenol
  • (2S,4R)-1-((S)-2-(1-fluorocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
  • (2S,4R)-1-((S)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
  • Phenolic VH101
  • Inhibitor,E3 ligase-recruiting Moiety,inhibit,VHL ligand3,Ligands for E3 Ligase,VH032 cyclopropane F,VH032cyclopropaneF,VHL ligand-3,VH-032-cyclopropane-F
  • (2S,4R)-1-[(2S)-2-[(1-fluorocyclopropyl)formamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
  • 2306193-99-5
  • C26H33FN4O5S
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