OH-Chol Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
OH-Chol is a cationic cholesterol derivative. OH-Chol, as a component of lipoplexes with DOPE , has been used for siRNA delivery and gene silencing in MCF-7 cells, as well as in mice
via intravenous injection, resulting in lipoplex accumulation in the liver. It has also been used in cationic nanoparticles in combination with Tween 80 to transfect pDNA and siRNA into PC3 mouse xenografts
via intratumoral injection and with Tween 80 and folate-PEG
2000-DSPE in a KB mouse xenograft model for intratumoral gene delivery.
OH-Chol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte