Monoclonal Anti-RAD23B, (C-terminal) antibody produced in mouse Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. (provided by RefSeq)
Monoclonal Anti-RAD23B, (C-terminal) antibody produced in mouse Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
