Kibdelone C Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Kibdelone C is a member of a family of natural heterocyclic polyketides first isolated from a soil actinomycete,
Kibdelosporangium. Kibdelones have been described as having potent and selective cytotoxicity against a panel of human tumor cell lines, and kibdelone C has low nanomolar effectiveness in these assays. Kibdelone C disrupts the actin cytoskeleton without directly binding actin or affecting its polymerization
in vitro.
Verwenden
Kibdelone C is the major analogue of a potent antitumour complex isolated from Kibdelosporangium sp.. Structurally, kibdelone C is related to lysolipin and albofungin, however no comparative investigation of this class has been reported. The mode of action and pharmacology of the kibdelones has received little attention.
Kibdelone C Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
