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Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-

Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Struktur
1132709-16-0
CAS-Nr.
1132709-16-0
Englisch Name:
Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
Synonyma:
Bortizomib SR-OH;(1S,2R)-BortezoMib;Bortezomib (1R,2R)Isomer;Bortezomib S,R Enantiomer;Bortezomib (1S, 2R)-Isomer;(1S,2R)-Bortezomib Impurity;Bortezomib S,R-Isomer Impurity;Bortezomib impurities (R, S-isomer);Bortezomib Impurity (1S,2R - Isomer);Bortezomib impurity 2/(1S,2R)-Bortezomib
CBNumber:
CB02677165
Summenformel:
C19H25BN4O4
Molgewicht:
384.24
MOL-Datei:
1132709-16-0.mol

Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Eigenschaften

Dichte
1.214±0.06 g/cm3(Predicted)
L?slichkeit
Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
9.66±0.43(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Stabilit?t:
Hygroscopic, Light sensitive, Moisture sensitive

Sicherheit

Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(1S,3R)-Bortezomib is an diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway

Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 64)Lieferanten
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  • Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
  • (1S,2R)-BortezoMib
  • (S)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butylboronic acid
  • N-(2-Pyrazinecarbonyl)-D-phenylalanine-D-leucine boronic anhydride
  • Bortezomib Impurity (1S,2R - Isomer)
  • Bortezomib impurity 2/(1S,2R)-Bortezomib
  • Bortezomib (1R,2R)Isomer
  • (1S,2R)-Bortezomib Impurity
  • Bortezomib impurities (R, S-isomer)
  • Bortezomib (1S, 2R)-Isomer
  • (1s) - 3-methyl-1 - [(2R) - 1-oxo-3-phenyl-2 - [(pyrazinoyl) - amino] propyl] amino] butyl] boric acid
  • Bortizomib SR-OH
  • Bortezomib S,R-Isomer Impurity
  • (1S,2R) BortezomibQ: What is (1S,2R) Bortezomib Q: What is the CAS Number of (1S,2R) Bortezomib Q: What is the storage condition of (1S,2R) Bortezomib Q: What are the applications of (1S,2R) Bortezomib
  • Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2
  • Bortezomib S,R Enantiomer
  • 1132709-16-0
  • Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
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