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Tubulin Polymerization Inhibitor II

Tubulin Polymerization Inhibitor II Struktur
1151995-69-5
CAS-Nr.
1151995-69-5
Englisch Name:
Tubulin Polymerization Inhibitor II
Synonyma:
Tubulin inhibitor 9;Tubulin Polymerization Inhibitor II;2H-Indol-2-one, 1,3-dihydro-6-methoxy-3-[(3,4,5-trimethoxyphenyl)methylene]-
CBNumber:
CB02501835
Summenformel:
C19H19NO5
Molgewicht:
341.36
MOL-Datei:
1151995-69-5.mol

Tubulin Polymerization Inhibitor II Eigenschaften

Siedepunkt:
549.5±50.0 °C(Predicted)
Dichte
1.241±0.06 g/cm3(Predicted)
storage temp. 
+2C to +8C
Aggregatzustand
Yellow solid
pka
12.16±0.20(Predicted)

Sicherheit

Tubulin Polymerization Inhibitor II Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Tubulin Polymerization Inhibitor II is a Tubulin inhibitor.

Allgemeine Beschreibung

A cell-permeable, SU5416- (Cat. Nos. 676487 and 676498) derived combretastatin A-4 (Cat. No. 234200) analog that acts as an effective anti-microtubule agent (IC50 = 4.5 μM in inhibiting polymerization of purified porcine brain tubulin) and displays extremely potent anti-proliferative activity towards various cancer cell lines (GI50<10 nM for 46 lines among a 53 NCI panel tested).

Biochem/physiol Actions

Cell permeable: yes

Tubulin Polymerization Inhibitor II Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Tubulin Polymerization Inhibitor II Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 7)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
Jinan ponder chemical co. LTD 0531-0000
thinklifescience@163.com China 19689 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44806 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761
486064515@qq.com China 4420 58

  • Tubulin Polymerization Inhibitor II
  • 2H-Indol-2-one, 1,3-dihydro-6-methoxy-3-[(3,4,5-trimethoxyphenyl)methylene]-
  • Tubulin inhibitor 9
  • 1151995-69-5
  • Angiogenesis and Metastasis
  • Growth Factors and Cytokines
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