Tubulin Polymerization Inhibitor II Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Tubulin Polymerization Inhibitor II is a Tubulin inhibitor.
Allgemeine Beschreibung
A cell-permeable, SU5416- (Cat. Nos. 676487 and 676498) derived combretastatin A-4 (Cat. No. 234200) analog that acts as an effective anti-microtubule agent (IC
50 = 4.5 μM in inhibiting polymerization of purified porcine brain tubulin) and displays extremely potent anti-proliferative activity towards various cancer cell lines (GI
50<10 nM for 46 lines among a 53 NCI panel tested).
Biochem/physiol Actions
Cell permeable: yes
Tubulin Polymerization Inhibitor II Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte