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1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE

1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE Struktur
154130-99-1
CAS-Nr.
154130-99-1
Englisch Name:
1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
Synonyma:
PD 144418;PD 144418 OXALATE;Pyridine,1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propyl-;1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
CBNumber:
CB02446510
Summenformel:
C18H22N2O
Molgewicht:
282.38
MOL-Datei:
154130-99-1.mol

1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE Eigenschaften

Siedepunkt:
453.2±45.0 °C(Predicted)
Dichte
1.067±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at RT
L?slichkeit
<18.62mg/ml in DMSO
Aggregatzustand
solid
pka
8.10±0.40(Predicted)
Farbe
Off-white

Sicherheit

1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

PD 144418 is high affinity, selective σ1 ligand (Ki values are 0.08 and 1377 nM for σ1 and σ2 respectively). PD 144418 displays no significant activity at a wide range of other receptors, ion channels and enzymes. PD 144418 antagonizes mescaline-induced scratching in mice following i.p. administration.

Biologische Aktivit?t

High affinity, selective σ 1 ligand (K i values are 0.08 and 1377 nM for σ 1 and σ 2 respectively). Displays no significant activity at a wide range of other receptors, ion channels and enzymes. Antagonizes mescaline-induced scratching in mice following i.p. administration.

1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 27)Lieferanten
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TargetMol Chemicals Inc.

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Chemsky (shanghai) International Co.,Ltd 021-50135380
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ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185
sales-cpd@caerulumpharma.com China 3466 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60

  • PD 144418 OXALATE
  • 1,2,3,6-TETRAHYDRO-5-[3-(4-METHYLPHENYL)-5-ISOXAZOLYL]-1-PROPYLPYRIDINE OXALATE
  • PD 144418
  • Pyridine,1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propyl-
  • 154130-99-1
  • C18H22N2OC2H2O4
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  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pfizer Compounds
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