ANTI-GABABR2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
Biochem/physiol Actions
The gene GABBR2 (γ-aminobutyric acid (GABA) B receptor, 2) encodes a G-protein coupled receptor 3 that belongs to the GABA-B receptor subfamily. It forms a heterodimer with GABBR1 to produce an active complex called the GABAB receptor. The complex binds to GABA, a major inhibitory neurotransmitter, and mediates its modulatory actions. It negatively regulates neuronal activity via the activation of G-protein-coupled second-messenger systems that are involved in the regulation of the release of neurotransmitters. Polymorphism in this gene is associated with susceptibility to nicotine dependence.
ANTI-GABABR2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
