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Sitafloxacin Sesquihydrate

Sitafloxacin Sesquihydrate Struktur
163253-35-8
CAS-Nr.
163253-35-8
Englisch Name:
Sitafloxacin Sesquihydrate
Synonyma:
Sitafloxacin hydrate;DU 6859;DU-6859;Du 6859a;LS-184401;Sitafloxacin;SITAFLOXACIN;Sitafloxacin;Xitafloxacin;Unii-9td681796g
CBNumber:
CB01429828
Summenformel:
C19H20ClF2N3O4
Molgewicht:
427.83
MOL-Datei:
163253-35-8.mol

Sitafloxacin Sesquihydrate Eigenschaften

Schmelzpunkt:
145-147°C (dec.)
alpha 
589 -199.9°
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
L?slichkeit
Aqueous Base (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)
Aggregatzustand
Solid
Farbe
White to Off-White
Stabilit?t:
Hygroscopic
InChIKey
ANCJYRJLOUSQBW-UWQPBFEBNA-N
SMILES
N[C@@H]1CN(C2=C(C=C3C(=O)C(C(=O)O)=CN([C@@H]4C[C@@H]4F)C3=C2Cl)F)CC21CC2.O |&1:1,16,18,r|
CAS Datenbank
163253-35-8(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
HS Code  2941900000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Sitafloxacin Sesquihydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The fluoroquinolone antibacterial agent sitafloxacin hydrate was developed by Daiichi Sankyo and was approved and launched last year in Japan. Sitafloxacin’s mode of action is through inhibition of DNA gyrase and topoisomerase IV. It is indicated for the treatment of inflammatory infections such as laryngopharyngitis, adenoiditis, acute bronchitis, pneumonia, secondary infections due to chronic respiratory lesions, cystitis, pyelonephritis, urethritis, cervicitis, otitismedia, sinusitis, periodontitis, and pericoronitis and jaw inflammation. Due to its broad spectrum of potent antibacterial activity, sitafloxacin is expected to be clinically effective in treating severe cases of bacterial infection, relapse/recrudescence of infection and infections in which resistant bacteria are suspected to be the cause.

Chemische Eigenschaften

Off-White Solid

Verwenden

Sitafloxacin is a new-generation, broad-spectrum oral fluoroquinolone antibiotic. It is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in

Nebenwirkungen

The most commonly reported adverse reactions include rash, dizziness, headache, diarrhea, loose stool, stomach discomfort, abdominal bloating, abdominal pain, constipation, indigestion, nausea and stomatitis.

Sitafloxacin Sesquihydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Sitafloxacin Sesquihydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 187)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Suzhou Chukai Pharma Tech Co.,Ltd
+8615062531973
2279973922@qq.com China 391 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12834 58
Hebei Mojin Biotechnology Co.,Ltd
+86-15028179902
angelia@hbmojin.com China 1176 58
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 - 03@
sales03@shyrchem.com CHINA 738 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd.
0431-80514535 13634302652
Extension@chemextension.com CHINA 967 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845
sales@amoychem.com China 6383 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
Shanghai Yingrui Biopharma Co.,Ltd
21-33585366
export01@shyrchem.com CHINA 1319 58

163253-35-8()Verwandte Suche:


  • Sitafloxacin Sesquihydrate
  • 7-[(7S)-7-Amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxoquinoline-3-carboxylic acid hydrate (2:3)
  • Sitafloxacin
  • 3-Quinolinecarboxylic acid, 7-((7S)-7-amino-5-azaspiro(24)hept-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, hydrate (2:3)
  • 3-Quinolinecarboxylic acid, 7-(7-amino-5-azaspiro(24)hept-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, hydrate (2:3), (1R-(1alpha(S*),2alpha))-
  • Du 6859a
  • Unii-9td681796g
  • Sitafloxacin hydrate (2:3)
  • 7-[(7S)-7-AMino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Hydrate
  • 7-(7-amino-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-4-oxo-3-quinolinecarboxylic acid hydrate
  • DU 6859
  • DU 6859A; DU 6859; DU-6859; LS-184401
  • DU-6859
  • LS-184401
  • Sitafloxacin Impurity 24
  • sitafloxacin hydrate Impurity 24
  • 7-[(4S)-4-amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxo-quinoline-3-carboxylic acid hydrate
  • 7-((S)-7-amino-5-azaspiro
  • DU6859a hydrate
  • 7-((S)-7-Amino-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Sesquihydrate
  • SITAFLOXACIN USP/EP/BP
  • Sitafloxacin 1.5Hydrate (DU6859a)
  • Sitafloxacin hydrate
  • 7-((S)-7-amino-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrate
  • 3-Quinolinecarboxylic acid, 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-, hydrate (2:3) (9CI, ACI)
  • 7-[(7S)-7-amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-Quinolinecarboxylic acid hydrate (2:3) (9CI ACI)
  • 7-(7S)-7-Amino-5-azaspiro2.4hept-5-yl-8-chloro-6-fluoro-1-(1R,2S)-2-fluoro-cyclopropyl-1,4-dihydro-4-oxo-quinolin-3-carboxylic acid hydrate (2:3)
  • SITAFLOXACIN
  • Sitafloxacin
  • Xitafloxacin
  • DU-6859a|||DU6859a hydrate
  • 163253-35-8
  • C19H18ClF2N3O315H2O
  • 2C19H18ClF2N3O33H2O
  • C19H18ClF2N3O3H2O
  • C19H18ClF2N3O332H2O
  • C19H20ClF2N3O4
  • DU 6859A, DU 6859, DU-6859, LS-184401
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Inhibitors
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