3-(2,4-dimethoxybenzylidene)anabaseine
|
|
|
- CAS-Nr.
- 156223-05-1
- Englisch Name:
- 3-(2,4-dimethoxybenzylidene)anabaseine
- Synonyma:
- DMXB;DMXB-A;DMBX-A;GTS-21HCl;GTS 21 2HCl;GTS-21 (DMXB-A);DMBX-anabaseine;GTS 21 2HCl(DMXBA);GTS21;GTS 21;GTS-21;GTS 21 2hydrochloride
- CBNumber:
- CB01372542
- Summenformel:
- C19H22Cl2N2O2
- Molgewicht:
- 0
- MOL-Datei:
- 156223-05-1.mol
|
3-(2,4-dimethoxybenzylidene)anabaseine Eigenschaften
- Schmelzpunkt:
- 216-217℃ (decomposition)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: >5mg/mL
- Aggregatzustand
- powder
- Farbe
- faint yellow to dark yellow
- InChIKey
- RPYWXZCFYPVCNQ-RVDMUPIBSA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
|
|
| RTECS-Nr. |
DW1764860 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
3-(2,4-dimethoxybenzylidene)anabaseine Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
GTS-21 has been used:
- as an α7 nicotinic acetylcholine receptors (nAChR) partial agonist to elucidate its anti-inflammatory effects in mouse macrophages
- to test its protective effect on the renal injury induced by lipopolysaccharide (LPS)
- to test its effect on microvascular inflammation?in endotoxemia induced by LPS
Biochem/physiol Actions
GTS-2, a derivative of anisine is an immunomodulatory drug. It is used for treating pancreatitis and septicemia. GTS-2 inhibits the pro-inflammatory cytokines especially the interleukin-6 (IL6) and tumor necrosis factor (TNF) in sepsis and endotoxemia.
3-(2,4-dimethoxybenzylidene)anabaseine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-(2,4-dimethoxybenzylidene)anabaseine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 92)Lieferanten
156223-05-1()Verwandte Suche:
- 3-(2,4-dimethoxybenzylidene)anabaseine
- 3-[(3E)-3-[(2,4-dimethoxyphenyl)methylidene]-5,6-dihydro-4H-pyridin-2-yl]pyridine dihydrochloride
- 3-(2,4-Dimethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl
- 3-(2,4)-DiMethoxybenzylidineanabaseine
- GTS-21 (DMXB-A)
- 3-(2,4-DiMethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl Dihydrochloride
- (3E)-3-[(2,4-Dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine dihydrochloride
- DMBX-anabaseine
- DMXB-A
- 3-(2,4-Dimethoxybenzylidene)-anabaseine dihydrochloride
- DMXB
- GTS 21 dihydrochloride
- 3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-Bipyridine Dihydrochloride
- GTS 21 2HCl
- GTS 21 2hydrochloride
- GTS 21 DIHYDROCHLORIDE;DMXB-A;DMBX-ANABASEINE
- GTS 21 2HCl(DMXBA)
- GTS21;GTS 21;GTS-21
- GTS-21 (hydrochloride)
- GTS-21HCl
- DMBX-A
- (E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride
- 3-(2,4-dimethoxybenzylidene)anabaseine / 99% / 156223-05-1 in sock
- GTS 21 dihydrochloride(DMXB-A)
- inhibit,5-hydroxytryptamine Receptor,anti?inflammatory,cognition,GTS-21,nAChR,GTS21 dihydrochloride,Serotonin Receptor,fibrosis,Inhibitor,GTS 21,5-HT Receptor,Nicotinic acetylcholine receptors,lung,injury,GTS21,pulmonary
- Dihydrochloride / 3-(2,4-dimethoxybenzylidene)anabaseine
- GTS-21 dihydrochloride (DMBX-A)
- (E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride
- (E)-3-(2,4-dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine hydrochloride
- 3-(2,4-Dimethoxy-benzyl)-3,4,5,6-tetrahydro-[2,3']bipyridinyl
- 156223-05-1
- C19H22Cl2N2O2
- C19H20N2O22HCl
- Inhibitors
