ANTI-EZRIN
|
|
|
- CAS-Nr.
- Englisch Name:
- ANTI-EZRIN
- Synonyma:
- Anti-CVL;ANTI-P81;ANTI-80K;Anti-VIL2;ANTI-EZRIN;Anti-Villin-2;ANTI-CYTOVILLIN;MOUSE ANTI-EZRIN;Anti-DKFZp762H157;Anti-EZR antibody produced in rabbit
- CBNumber:
- CB0136813
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
|
ANTI-EZRIN Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- buffered aqueous solution
ANTI-EZRIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
The antibody was used for detection of Ezrin by immunostaining, immunoblotting in human bladder cancer cells , immunohistochemistry, immunoprecipitation in kidney and colon adenocarcinoma cells and electron microscopy in astrocytes
Allgemeine Beschreibung
Ezrin is a member of the best studied member of the ERM family of proteins. The ERM family regulates the dynamic cell membrane functions such as endocytosis, exocytosis, and transmembrane and other cortical signalling pathways. Ezrin (molecular weight 80 kDa) interacts with transmembrane proteins and F-actin and mediate important signalling pathways including RhoA and Hedgehog signalling. Ezrin is also present in the microvillus surface of acid-secreting parietal cells of the gastric glands, where it presents as a family of isoelectric variants. By immunoelectron microscopy of human choriocarcinoma cells, ezrin is enriched just inside the plasma membrane of microvilli and less abundant on more planar aspects of the membrane.
Biochem/physiol Actions
Ezrin links the cytoskeleton to the plasma membrane, based on its amino acid sequence homologies with other cytoskeletal proteins. It regulates cell growth, migration, and cell adhesion. Ezrin is also implicated in cancer cell invasion and metastasis. The proteins of the ezrin family serve as tyrosine kinase phosphorylation substrates. They exhibit a growth factor receptor-specific pattern of phosphorylation. Ezrin is phosphorylated by epidermal growth factor receptor and platelet-derived growth factor receptor.
ANTI-EZRIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-EZRIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 14)Lieferanten
- MOUSE ANTI-EZRIN
- Anti-EZR (Ab-567) antibody produced in rabbit
- Anti-phospho-EZR (pTyr353) antibody produced in rabbit
- Anti-EZR (Ab-353) antibody produced in rabbit
- Anti-EZR antibody produced in rabbit
- Anti-VIL2
- Anti-Villin-2
- Anti-CVL
- Anti-DKFZp762H157
- Anti-EZRIN/VILLIN 2 antibody produced in goat
- Anti-CVIL antibody produced in rabbit
- Anti-CVL antibody produced in rabbit
- Anti-DKFZp762H157 antibody produced in rabbit
- Anti-FLJ26216 antibody produced in rabbit
- Anti-phospho-EZR (pThr567) antibody produced in rabbit
- ANTI-EZRIN
- ANTI-CYTOVILLIN
- ANTI-P81
- ANTI-80K
- Anti-80K, Anti-Cytovillin, Anti-p81
- Anti-Ezrin antibody produced in rabbit
- Monoclonal Anti-Ezrin antibody produced in mouse
- 3
- Alphabetical Index
- Antibodies to Actin-associated Proteins/MyosinAntibodies
- Antibodies to Cytoskeleton
- Cell Biology
- Clone Index
- EAntibodies
