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SMZ/TMP

SMZ/TMP Struktur
8064-90-2
CAS-Nr.
8064-90-2
Englisch Name:
SMZ/TMP
Synonyma:
TMP-SMX;SMZ/TMP;Septrim;Chemitrim;Trimforte;Trimethoprimsulfa;Co-Trimoxazole (CTX), 95%;Trimethoprim-Sulfamethoxazole;Sulfamethoxazole/Trimethoprim;TRIMETHOPRIM/SULPHAMETHOXAZOLE
CBNumber:
CB01105579
Summenformel:
C24H29N7O6S
Molgewicht:
543.6
MOL-Datei:
8064-90-2.mol

SMZ/TMP Eigenschaften

storage temp. 
-20°C
L?slichkeit
DMF: 10mg/mL,DMSO: 10mg/mL,DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL,Ethanol: 0.3mg/mL
Aggregatzustand
liquid
Farbe
colorless to faint yellow
BCS Class
4/4
EPA chemische Informationen
Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, mixt. with 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine (8064-90-2)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38-43
S-S?tze: 26-36/37
WGK Germany  3
RTECS-Nr. UV8240000
Giftige Stoffe Daten 8064-90-2(Hazardous Substances Data)
Toxizit?t LD50 orally in mice: 5513 mg/kg (Yamamoto)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

SMZ/TMP Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Cotrimoxazole is an antibiotic. Pseudomonas aeruginosa has a drug resistant rate of 66% in the years 2010-2013.

Weltgesundheitsorganisation (WHO)

The combination of sulfamethoxazole and trimethoprim (5:1) was introduced in 1971 for the treatment of a wide variety of bacterial infections. Its use has been associated with severe sensitivity reactions, many of which have been attributed to the sulphonamide component. Elderly people seem to be more vulnerable. The World Health Organization has no information further to the above concerning restrictive action taken on this combination.

Nebenwirkungen

Trimethoprim/sulfamethoxazole on a daily basis has a rapid onset of action but has rare associated side effects of bone marrow suppression and toxic epidermal necrolysis (TEN).
Nausea, vomiting, and anorexia are generally dose related. Hypersensitivity reactions (including Stevens-Johnson syndrome and hematologic reactions) occur in <5% of patients.

SMZ/TMP Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SMZ/TMP Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 17)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
BOC Sciences 		16314854226; +16314854226
 inquiry@bocsci.com United States 19741 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152
 Mandy@hangyubiotech.com China 10986 58
TargetMol Chemicals Inc. 		+8613564774135
 zijue.cai@tsbiochem.com United States 19885 58
Alfa Chemistry 1-516-6625404
support@alfa-chemistry.com United States 9171 60
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 11974 58
Shandong Mopai Biotechnology Co., Ltd 13070690626
 admin@mopaikeji.com China 10757 58
Shaanxi Istare Biotechnology Co., Ltd. 18682931470
 2142355700@qq.com China 4508 58
TargetMol Chemicals Inc. 15002134094
 marketing@targetmol.cn China 19704 58

8064-90-2()Verwandte Suche:

  • SMZ/TMP
  • Sulfamethoxazole/Trimethoprim
  • Trimethoprim-Sulfamethoxazole Combination
  • TRIMETHOPRIM/SULPHAMETHOXAZOLE
  • Chemitrim
  • Septrim
  • Cotrimoxazole, Ready Made Solution
  • TMP-SMX
  • Trimethoprim-Sulfamethoxazole
  • Co-Trimoxazole (CTX), 95%
  • Trimethoprimsulfa
  • Trimforte
  • 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine mixture with 4-amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide
  • 8064-90-2
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