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N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide

N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide Struktur
1808928-00-8
CAS-Nr.
1808928-00-8
Englisch Name:
N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide
Synonyma:
N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-(6-bromoimidazo[1,2-a]pyridin-2-yl)-
CBNumber:
CB010718311
Summenformel:
C11H10BrN3O
Molgewicht:
280.12
MOL-Datei:
1808928-00-8.mol

N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide Eigenschaften

Dichte
1.81±0.1 g/cm3(Predicted)
pka
9.83±0.20(Predicted)
InChI
InChI=1S/C11H10BrN3O/c12-8-3-4-10-13-9(6-15(10)5-8)14-11(16)7-1-2-7/h3-7H,1-2H2,(H,14,16)
InChIKey
LAKCXXIEOGRDJQ-UHFFFAOYSA-N
SMILES
C1(C(NC2=CN3C(=N2)C=CC(Br)=C3)=O)CC1

Sicherheit

N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Synthese

To a solution of 6-Bromoimidazo[1,2-a]pyridin-2-amine (73 g, 346 mmol) in CH2Cl2 (1.5 L) was added Et3N (42 g, 415 mmol). Cyclopropanecarbonyl chloride (41 g, 398 mmol) in CH2Cl2 (100 mL) was added dropwise at 0 C. After the addition was complete, the mixture was warmed to room temperature and stirred for 3 h. After the reaction was complete according to TLC, saturated K2CO3 solution (100 mL) was added to quench the reaction. The mixture was stirred for 2h. Yellow solids crushed out of the mixture were collected by filtration and dried to provide N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide as a yellow solid (97 g, 99%)N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide

N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 9)Lieferanten
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Shandong Libixi Biopharmaceutical Technology Co., Ltd. 15318973357
 1460285141@qq.com China 5759 58
  • N-(6-Bromoimidazo[1,2-a]pyridin-2-yl)cyclopropanecarboxamide
  • Cyclopropanecarboxamide, N-(6-bromoimidazo[1,2-a]pyridin-2-yl)-
  • 1808928-00-8
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