6-羥基-2-氨甲基嘌呤
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- CAS號:
- 10030-78-1
- 英文名:
- 6-HYDROXY-2-METHYLAMINOPURINE
- 英文別名:
- N2-METHYLGUANINE;2-(MethylaMino)-7H-purin-6-ol;6-HYDROXY-2-METHYLAMINOPURINE;2-(MethylaMino)-1H-purin-6(7H)-one;2-methylamino-3,7-dihydropurin-6-one;1,7-Dihydro-2-(methylamino)-6H-purin-6-one;2-(methylamino)-6,7-dihydro-3H-purin-6-one;6H-Purin-6-one,1,9-dihydro-2-(methylamino)-;Endogenous Metabolite,Inhibitor,Bacterial,2 (Methylamino) 1H purin 6(7H) one,2(Methylamino)1Hpurin6(7H)one,inhibit,DNA/RNA Synthesis
- 中文名:
- 6-羥基-2-氨甲基嘌呤
- 中文別名:
- N2-甲基鳥嘌呤;2-甲氨基-6-羥基嘌呤;6-羥基-2-氨甲基嘌呤;6-羥基-2-氨甲基嘌呤 10G;化合物 N2-METHYLGUANINE;2-(甲氨基)-3H-嘌呤-6(7H)-酮;2-(甲基氨基)-1H-嘌呤-6(7H)-酮;2-(甲基氨基)-6,7-二氫-3H-嘌呤-6-酮
- CBNumber:
- CB8704274
- 分子式:
- C6H7N5O
- 分子量:
- 165.15
- MOL File:
- 10030-78-1.mol
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6-羥基-2-氨甲基嘌呤化學(xué)性質(zhì)
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熔點:
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>300 °C (decomp)
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密度:
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1.79±0.1 g/cm3(Predicted)
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儲存條件:
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4°C, Inert atmosphere
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溶解度:
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DMSO : < 1 mg/mL (insoluble or slightly soluble)
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形態(tài):
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Solid
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酸度系數(shù)(pKa):
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9.86±0.20(Predicted)
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顏色:
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Light yellow to khaki
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6-羥基-2-氨甲基嘌呤性質(zhì)、用途與生產(chǎn)工藝
2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) 是經(jīng)過修飾的核苷,是在人體液中存在的內(nèi)源性甲基化核苷。
Human Endogenous Metabolite
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2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is found within both helical and looped regions of RNA secondary structure, and it can exist in either the s-cis or the s-trans rotamer. If there is a rotational preference for the methyl group, the effect of 2-(Methylamino)-1H-purin-6(7H)-one substitution may be specific to the sequence context depending upon which face of the base participates in hydrogen bonding. 2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is the principal kinetic barrier for reverse transcription in the 1340 bases proximal to the 5' end of
E. coli
16S rRNA. Transcription intermediates correspond to attenuation at the positions of 2-(Methylamino)-1H-purin-6(7H)-one in the rRNA sequence. The relaxation time for elongation of the cDNA through m2G is approximately 3 min.
6-羥基-2-氨甲基嘌呤
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS編號 | 包裝 | 價格 |
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2024/11/08 | HY-101412 | 2-(Methylamino)-1H-purin-6(7H)-one | | 1 mg | 520元 |
2024/11/08 | HY-101412 | 6-羥基-2-氨甲基嘌呤 2-(Methylamino)-1H-purin-6(7H)-one | 10030-78-1 | 5mg | 1300元 |
10030-78-1, 6-羥基-2-氨甲基嘌呤 相關(guān)搜索:
- 抑制劑
- 高端化學(xué)
- 化合物 N2-METHYLGUANINE
- 2-(甲氨基)-3H-嘌呤-6(7H)-酮
- N2-甲基鳥嘌呤
- 2-(甲基氨基)-6,7-二氫-3H-嘌呤-6-酮
- 6-羥基-2-氨甲基嘌呤 10G
- 2-(甲基氨基)-1H-嘌呤-6(7H)-酮
- 2-甲氨基-6-羥基嘌呤
- 6-羥基-2-氨甲基嘌呤
- 10030-78-1
- Endogenous Metabolite,Inhibitor,Bacterial,2 (Methylamino) 1H purin 6(7H) one,2(Methylamino)1Hpurin6(7H)one,inhibit,DNA/RNA Synthesis
- 2-(methylamino)-6,7-dihydro-3H-purin-6-one
- 6H-Purin-6-one,1,9-dihydro-2-(methylamino)-
- 1,7-Dihydro-2-(methylamino)-6H-purin-6-one
- 2-methylamino-3,7-dihydropurin-6-one
- 2-(MethylaMino)-1H-purin-6(7H)-one
- 2-(MethylaMino)-7H-purin-6-ol
- 6-HYDROXY-2-METHYLAMINOPURINE
- N2-METHYLGUANINE