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  2. Anti-infection Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. Bacterial DNA/RNA Synthesis Endogenous Metabolite
  4. 2-(Methylamino)-1H-purin-6(7H)-one

2-(Methylamino)-1H-purin-6(7H)-one  (Synonyms: N2-methylguanine)

目錄號: HY-101412 純度: ≥98.0%
COA 產(chǎn)品使用指南

2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) 是經(jīng)過修飾的核苷，是在人體液中存在的內(nèi)源性甲基化核苷。

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2-(Methylamino)-1H-purin-6(7H)-one Chemical Structure

2-(Methylamino)-1H-purin-6(7H)-one Chemical Structure

CAS No. : 10030-78-1

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥520
In-stock
5 mg ￥1300
In-stock
10 mg ￥2000
In-stock
25 mg ￥3538
In-stock
50 mg ￥5000
In-stock
100 mg 現(xiàn)貨 詢價
200 mg   詢價  
500 mg   詢價  

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Customer Review

MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻(xiàn)

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

2-(Methylamino)-1H-purin-6(7H)-one (N2-Methylguanine) is a modified nucleoside. 2-(Methylamino)-1H-purin-6(7H)-one is an endogenous methylated nucleoside found in human fluids.

IC50 & Target

Human Endogenous Metabolite

 

體外研究
(In Vitro)

2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is found within both helical and looped regions of RNA secondary structure, and it can exist in either the s-cis or the s-trans rotamer. If there is a rotational preference for the methyl group, the effect of 2-(Methylamino)-1H-purin-6(7H)-one substitution may be specific to the sequence context depending upon which face of the base participates in hydrogen bonding[1]. 2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) is the principal kinetic barrier for reverse transcription in the 1340 bases proximal to the 5' end of E. coli 16S rRNA. Transcription intermediates correspond to attenuation at the positions of 2-(Methylamino)-1H-purin-6(7H)-one in the rRNA sequence. The relaxation time for elongation of the cDNA through m2G is approximately 3 min[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

165.15

Formula

C6H7N5O
CAS 號
性狀

固體

顏色

Light yellow to khaki

中文名稱

N2-甲基鳥嘌呤
結(jié)構(gòu)分類
初始來源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性數(shù)據(jù)
細(xì)胞實驗： 

Ethanol 中的溶解度 : < 1 mg/mL (insoluble)

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

H2O 中的溶解度 : < 0.1 mg/mL (insoluble)

  • 摩爾計算器

  • 稀釋計算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量
=
濃度
×
體積
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

×
體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

動物溶解方案計算器
請輸入動物實驗的基本信息：

給藥劑量

mg/kg

動物的平均體重

g

每只動物的給藥體積

μL

動物數(shù)量

只
由于實驗過程有損耗，建議您多配一只動物的量
計算結(jié)果
工作液所需濃度 : mg/mL
純度 & 產(chǎn)品資料
參考文獻(xiàn)
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
2-(Methylamino)-1H-purin-6(7H)-one
目錄號：
HY-101412
需求量：