959-23-9
中文名稱
4'-甲氧基查耳酮
英文名稱
4'-METHOXYCHALCONE
CAS
959-23-9
EINECS 編號(hào)
213-495-5
分子式
C16H14O2
MDL 編號(hào)
MFCD00008407
分子量
238.28
MOL 文件
959-23-9.mol
更新日期
2023/03/20 19:41:21
959-23-9 結(jié)構(gòu)式
基本信息
中文別名
4'-甲氧基查耳酮,97%1-(4-甲氧基苯基)-3-苯基丙-2-烯-1-酮
英文別名
1-(4-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE2-BENZYLIDENE-4'-METHOXYACETOPHENONE
4'-METHOXYCHALCONE
(E)-1-(4-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE
METHOXYCHALCONE, 4'-
RARECHEM AM UC 0609
alpha-styryl p-anisyl ketone
4'-METHOXYCHALCONE 97%
Benzylidene(4-methoxyacetophenone)
4'-Methoxychalcone,97%
1-(4-Methoxyphenyl)-3-phenyl-2-propen-1-one
4-Methoxyphenylstyryl ketone
Styryl(4-methoxyphenyl) ketone
β-Phenyl-4'-methoxyacrylophenone
所屬類別
生物化工：提取物物理化學(xué)性質(zhì)
熔點(diǎn)101-103 °C(lit.)
沸點(diǎn)397.5±42.0 °C(Predicted)
密度1.114±0.06 g/cm3(Predicted)
形態(tài)Solid
顏色White to light yellow
水溶解性Soluble in dichloromethane and methanol. Insoluble in water.
BRN644640
LogP4.180 (est)
CAS 數(shù)據(jù)庫(kù)959-23-9(CAS DataBase Reference)
安全數(shù)據(jù)
4'-甲氧基查耳酮價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | B22158 | 4’-甲氧基查耳酮, 97% 4'-Methoxychalcone, 97% | 959-23-9 | 5g | 298元 |
| 2024/11/08 | B22158 | 4’-甲氧基查耳酮, 97% 4'-Methoxychalcone, 97% | 959-23-9 | 25g | 736元 |
| 2024/11/08 | B22158 | 4’-甲氧基查耳酮, 97% 4'-Methoxychalcone, 97% | 959-23-9 | 100g | 1496元 |
常見(jiàn)問(wèn)題列表
生物活性
4'-Methoxychalcone存在于柑橘屬植物中，是一種查耳酮衍生物，具有多種藥理活性，如抗腫瘤和消炎活性。靶點(diǎn)
PPARγ
體外研究
4'-Methoxychalcone (5 μM; 8 days) markedly increases the mRNA expression of adipogenic genes during adipocyte differentiation, PPARγ, aP2, FAS, adiponectin and GluT 4. 4'-Methoxychalcone (5 μM; 8 days) reduces the upregulated mRNA expression of IL-6, PAI-1, and MCP-1 by TNF-α in preadipocyte 3T3-L1 cells. 4'-Methoxychalcone (5 μM; 0-8 days) causes an increase in PPARγ expression during differentiation, while C/EBPβ protein expression is relatively unaffected.
RT-PCR
| Cell Line: | Preadipocyte 3T3-L1 cells |
| Concentration: | 5 μM |
| Incubation Time: | 0 day; 2 days; 4 days; 6 days; 8 days |
| Result: | Increased the mRNA expression of all adipogenic genes, except GluT1 in adipocyte. |
Western Blot Analysis
| Cell Line: | Preadipocyte 3T3-L1 cells |
| Concentration: | 5 μM |
| Incubation Time: | 8 days |
| Result: | Increased PPARγ expression in adipocyte. |