87051-43-2
87051-43-2 結(jié)構(gòu)式
基本信息
利坦絲林
利坦絲林 25MG
6-(2-(4-(雙(4-氟苯基)亞甲基)哌啶-1-基)乙基)-7-甲基-5H-噻唑并[3,2-A]嘧啶-5-酮
Tiserton
RITANSERIN
RITANSERIN SEROTONIN ANTAGONIST
6-[2-[4-[Bis(4-fluorophenyl)Methylidene]piperidin-1-yl]ethyl]-7-Methyl-[1,3]thia
6-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimi
6-[2-[4-[BIS(4-FLUOROPHENYL)-METHYLENE]-1-PIPERIDINYL]-ETHYL]-5H-THIAZOLO[3,2-A]PYRIMIDIN-5-ONE
6-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)-ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin
6-[2-[4-[Bis(4-fluorophenyl)methylene]-piperidino]ethyl]-7-methyl-5H-thiazolo-[3,2-a]pyrimidin-5-one
6-[2-[4-[Bis(4-fluorophenyl)methylene]piperidin-1-yl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
常見(jiàn)問(wèn)題列表
|
5-HT 2 Receptor 0.9 nM (IC 50 ) |
H 1 Receptor 35 nM (IC 50 ) |
D 2 Receptor 70 nM (IC 50 ) |
Adrenergic α1 97 nM (IC 50 ) |
Adrenergic α2 150 nM (IC 50 ) |
Ritanserin (R 55667) is a highly potent, relatively selective, long acting antagonist of 5-HT2 receptor, with an IC 50 of 0.9 nM, less active on Histamine-H 1 (IC 50 , 35 nM), Dopamine-D 2 (IC 50 , 70 nM), Adrenergic-α 1 (IC 50 , 97 nM), Adrenergic-α 2 receptor (IC 50 , 150 nM).