80321-69-3
基本信息
七葉膽苷XVI
七葉膽苷XVⅡ
七葉膽苷XVII
絞股藍(lán)皂甙XVII
絞股藍(lán)皂苷XVII
七葉膽皂苷XVII
七葉膽苷XVII對(duì)照品,
七葉膽苷XVII(標(biāo)準(zhǔn)品)
七葉膽苷XVII(絞股藍(lán)皂苷XVII)
Gynosaponin S
Gypenoside ⅩⅦ
GYPENOSIDE-XVII
Gypenoside XVII (Gynosaponin S)
3β-(β-D-Glucopyranosyloxy)-12β-hydroxy-5α-dammar-24-en-20-yl 6-O-β-D-glucopyranosyl-β-D-glucopyranoside
β-D-Glucopyranoside, (3β,12β)-3-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-β-D-glucopyranosyl-
(3beta,12beta)-3-(beta-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
物理化學(xué)性質(zhì)
應(yīng)用領(lǐng)域
藥理藥效:絞股藍(lán)總皂甙具有人參皂甙的適應(yīng)原作用,其藥理作用大致可分為如下方面:1、消炎,抗腸、胃潰瘍和腫瘍。2、防癌抗癌。3、活化人體正常細(xì)胞(起增強(qiáng)體力、活力、耐力、恢復(fù)疲勞和延長(zhǎng)壽命的作用)。4、鎮(zhèn)靜和寧神。5、調(diào)節(jié)類(lèi)脂代謝。
常見(jiàn)問(wèn)題列表
Human Endogenous Metabolite
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The ability of Gypenoside XVII (GP-17) to prevent Ox-LDL-induced cytotoxicity is detected by cell viability assays. Gypenoside XVII does not demonstrate any cytotoxicity in HUVECs. Gypenoside XVII can protect HUVECs against Ox-LDL-induced apoptosis. Gypenoside XVII dose-dependently mitigates the toxic effect of Ox-LDL on HUVEC viability. The viability of HUVECs is significantly higher than that of other groups at 50 μg/mL Gypenoside XVII .
Body weights are measured as physical measures of hormone bioactivity. Mean body weights are significantly higher in every group compared to that of the control, but there is no significant difference in body weight between the different treatments during the 10-week feeding. The mouse plasma lipid levels are also measured at the end of 10 weeks of a high-fat diet. Circulating levels of total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) are significantly increased in the treated groups of ApoE -/- mice compared with those of the C57BL/6J control group; Gypenoside XVII (GP-17) and Probucol treatment substantially decreases both of these parameters relative to those of the ApoE -/- model group.