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71914-80-2

中文名稱 S-腺苷甲硫氨酸對(duì)甲苯磺酸鹽
CAS 71914-80-2
分子式 C15H23N6O5S.C7H7O3S
分子量 570.64
MOL 文件 71914-80-2.mol
更新日期 2024/12/20 18:42:48
71914-80-2 結(jié)構(gòu)式 71914-80-2 結(jié)構(gòu)式

基本信息

中文別名
腺苷蛋氨酸甲苯磺酸鹽
S-腺苷甲硫氨酸對(duì)甲苯磺酸鹽
S-腺甙甲硫氨酸對(duì)甲苯磺酸鹽
S-腺苷甲硫氨酸對(duì)甲苯磺酸鹽 17176-17-9/
S-腺苷甲硫氨酸對(duì)甲苯磺酸鹽(S-腺甙甲硫氨酸對(duì)甲苯磺酸鹽)
英文別名
SAM-E
S-ADENOSYLMETHIONINE TOSYLATE
S-ADENOSYL-L-METHIONINE (SAME)
S-Adenosyl-L-methionine tosylate
S-(5'-ADENOSYL)-L-METHIONINETOLUENE- &
S-Adenosyl-L-methionine tosylate USP/EP/BP
S-(5'-ADENOSYL)-L-METHIONINE P-TOLUENESULFONATE
S-(5''-Adenosyl)-L-methionine-4-toluenesulfonate
S-(5'-ADENOSYL)-L-METHIONINE TOLUENE-4-SULFONATE
[(3S)-3-amino-3-carboxypropyl]-[[(2S,3R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium:4-methylbenzenesulfonate

物理化學(xué)性質(zhì)

儲(chǔ)存條件−20°C
溶解度H2O: 0.1 g/mL, clear

安全數(shù)據(jù)

WGK Germany3
S-腺苷甲硫氨酸對(duì)甲苯磺酸鹽價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08HY-B0617AS-腺苷甲硫氨酸對(duì)甲苯磺酸鹽
S-Adenosyl-L-methionine tosylate
71914-80-250mg750元
2024/11/08HY-B0617AS-腺苷甲硫氨酸對(duì)甲苯磺酸鹽
S-Adenosyl-L-methionine tosylate
71914-80-210mM * 1mLin Water825元
2024/11/08HY-B0617AS-腺苷甲硫氨酸對(duì)甲苯磺酸鹽
S-Adenosyl-L-methionine tosylate
71914-80-2100mg1300元

常見問題列表

生物活性
S-Adenosyl-L-methionine tosylate (S-Adenosyl methionine tosylate) 是通過蛋氨酸腺苷轉(zhuǎn)移酶的作用由蛋氨酸和 ATP 內(nèi)源性生產(chǎn)的,是一種重要的具有口服活性的甲基供體。S-Adenosyl-L-methionine tosylate 是一種具有有效的抗抑郁和鎮(zhèn)痛作用的膳食補(bǔ)充劑,并可用于肝病和骨關(guān)節(jié)炎的研究。
體外研究

S-Adenosyl-L-methionine (Ademetionine) is involved in three main metabolic pathways: 1) methylation, as the principal source of methyl groups in the body; 2) transsulfuration, S-Adenosyl-L-methionine forms S-Adenosylhomocysteine (SAH) and then converted to homocysteine (Hcy) which can be converted to cystathionine then to cysteine and the sulfate (SO4) donated to other metabolic intermediates; and 3) aminopropylation, as S-Adenosyl-L-methionine plays an important role in the synthesis of polyamines which can eventually form and recycle methionine.
In vitro studies using human articular chondrocytes have shown S-Adenosyl-L-methionine-induced increases in proteoglycan synthesis and proliferation rates in rabbits.

體內(nèi)研究

Mice lacking methionine adenosyltransferase 1a (Mat1a) have reduced hepatic S-Adenosyl-L-methionine levels and develop oxidative stress, steatohepatitis, and hepatocellular carcinoma (HCC). However, injury and HCC also occur if hepatic S-Adenosyl-L-methionine level is excessive chronically. Thus a normal hepatic S-Adenosyl-L-methionine level is necessary to maintain liver health and prevent injury and HCC.

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