59-33-6
59-33-6 結(jié)構(gòu)式
基本信息
馬來(lái)酸新安替根
蘋果酸吡納明
蘋果酸新按特甘
順丁烯二酸吡納明
馬來(lái)酸美吡拉敏
MEPYRAMINE MALEATE
MEPYRAMINE MALEATE SALT
N-[4-METHOXY-PHENYL]METHYL-N',N'-DIMETHYL-N[2-PYRIDINYL]-1,2-ETHANEDIAMINE MALEATE SALT
N-(P-METHOXYBENZYL)-N',N'-DIMETHYL-N-2-PYRIDYLETHYLENEDIAMINE MALEATE
PYRANISAMINE MALEATE
PYRILAMINE MALEATE
PYRILAMINE MALEATE SALT
(z)-2-butenedioat
1,2-Ethanediamine,N-[(4-methoxyphenyl)methyl]-N’,N’-dimethyl-N-2-pyridinyl-,(Z)-2-butenedioate(1:1)
2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)pyridinebimaleate
2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-pyridinmaleate(1:1)
2786r.p.maleate
2-ethanediamine,n-[(4-methoxyphenyl)methyl]-n’,n’-dimethyl-n-2-pyridinyl-(
anisopyradamine
anthisanmaleate
antihist
diaminidemaleate
minihist
n-((4-methoxyphenyl)methyl)-n,n’-dimethyl-n-2-pyridinyl-2-ethanediamine
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | P2369 | 馬來(lái)酸吡拉明 Pyrilamine Maleate | 59-33-6 | 5g | 230元 |
| 2024/11/08 | HY-B1281 | N-[(4-甲氧苯基)甲基]-N-(2-吡啶基)-N’,N’-二甲基-乙二胺馬來(lái)酸鹽 Mepyramine maleate | 59-33-6 | 100mg | 500元 |
| 2024/11/08 | S4382 | N-[(4-甲氧苯基)甲基]-N-(2-吡啶基)-N’,N’-二甲基-乙二胺馬來(lái)酸鹽 Pyrilamine Maleate | 59-33-6 | 25mg | 794.78元 |
常見(jiàn)問(wèn)題列表
Kd: 0.8 nM (Histamine H1 receptor), 5200 nM (Histamine H2 receptor), >3000 nM (Histamine H3 receptor)
pKd: 9.4 (Histamine H1 receptor)
Mepyramine maleate is an antagonist of histamine H1 receptor, with K d s of 0.8 nM, 5200 nM and >3000 nM for H1, H2, and H3 receptor, respectively, and a pK d of 9.4 for H1 receptor. Mepyramine binds to the H1 receptor with different K d s in Guinea pig brain (0.8 nM), rat brain (9.1 nM) and DDT1-MF-2 and BC3H1 cell (276 nM). Mepyramine decreases the InsP levels in CHO-gpH1 cells, with log EC 50 of -7.94 ± 0.11, and reduces the the maximal response to ATP in CHO-gpH1 cells.
Mepyramine obviously decreases the second phase of nociceptive response via i.p at 10 and 20 mg/kg, but shows no significant effect at 5 mg/kg in rats.