5874-97-5
5874-97-5 結(jié)構(gòu)式
基本信息
硫酸奧西那林
硫酸奧昔帕林
異丙喘寧硫酸鹽
奧西那林硫酸鹽
硫酸奧腎上腺素
奧西那林半硫酸鹽
硫酸奧西那林 標(biāo)準(zhǔn)品
硫酸奧西那林(異丙喘寧)
奧西那林半硫酸鹽 標(biāo)準(zhǔn)品
th-152
alupent
metaprel
Astmopent
novasmasol
ORCIPRENALINE SULFATE
METAPROTERENOL SULFATE
dl-Orciprenaline sulfate
METAPROTERENOLSULFATE,USP
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-B1276 | 硫酸奧西那林 Metaproterenol hemisulfate | 5874-97-5 | 50mg | 500元 |
| 2024/11/08 | HY-B1276 | 硫酸奧西那林 Metaproterenol hemisulfate | 5874-97-5 | 10mM * 1mLin DMSO | 550元 |
| 2024/11/08 | HY-B1276 | 硫酸奧西那林 Metaproterenol hemisulfate | 5874-97-5 | 100mg | 700元 |
常見(jiàn)問(wèn)題列表
IC50: 68 nM (β2-adrenergic receptor)
Metaproterenol (10 μM; 74 hours; THP-1 cells and bone marrow macrophages) treatment enhances β-arrestin2 and its interaction with IκBα in high glucose-induced THP-1 cells and bone marrow macrophages.
Metaproterenol (10 μM; 74 hours; THP-1 cells and bone marrow macrophages) treatment leads to downregulation of NF-κB in high glucose-induced THP-1 cells and bone marrow macrophages.
Western Blot Analysis
| Cell Line: | THP-1 cells and bone marrow macrophages |
| Concentration: | 10 μM |
| Incubation Time: | 74 hours |
| Result: | Enhanced β-arrestin2 and its interaction with IκBα. |
RT-PCR
| Cell Line: | THP-1 cells and bone marrow macrophages |
| Concentration: | 10 μM |
| Incubation Time: | 74 hours |
| Result: | Led to downregulation of NF-κB. |
Treatment of Zucker diabetic fatty rats with Metaproterenol for 12 weeks attenuates monocyte activation as well as pro-inflammatory and pro-fibrotic responses in the kidneys and heart. Thus, Metaproterenol might has protective effects against diabetic renal and cardiovascular complications.