578-74-5
中文名稱
芹甙元-7-葡萄糖苷
英文名稱
Apigenin 7-glucoside
CAS
578-74-5
EINECS 編號
209-430-5
分子式
C21H20O10
MDL 編號
MFCD00016787
分子量
432.38
MOL 文件
578-74-5.mol
更新日期
2024/12/20 18:41:59
578-74-5 結(jié)構(gòu)式
基本信息
中文別名
芹菜素-7-葡萄甙芹菜苷配基-7-O-葡糖苷
芹菜素-7-葡萄糖苷
芹菜甙元(芹菜素)-7-葡萄糖甙
芹菜甙元(芹菜素)-7-O-葡萄糖甙
芹菜素-7- O -葡萄糖苷
大波斯菊苷
芹菜甙元-7- 葡萄糖甙
芹菜甙元-7- O-葡萄糖甙
芹甙元-7-葡萄糖苷
英文別名
OSMIINCOSMETIN
COSMOSIIN
APIGETRIN
Cosemetin
Cosmosioside
APIGENIN-7-GLUCOSIDE
Apigetrin, Cosmosiin
APIGENIN-7-O-GLUCOSIDE
Apigenin 7-β-D-glucoside
Apigenin 7-b-D-glucoside
Apigenin-7-O-β-D-glucoside
Apigenin 7-beta-D-glucoside
APIGENIN-7-O-GLUCOSIDE hplc
7-o-(beta-D-Glucosyl)apigenin
APIGENIN-7-O-GLUCOSIDE WITH HPLC
Apigenin-7-O-β-D-glucopyranoside
Apigenin, 7-beta-D-glucopyranoside
APIGENIN-7-GLUCOSIDE (COSMOSIIN)(P)
APIGENIN-7-O-GLUCOSIDE (COSMOSIIN)(P)
APIGENIN-7-O-GLUCOSIDE (COSMOSIIN)(SH)
Apigenin 7-glucoside SynonyMs:Apigetrin
7-O-BETA-D-GLUCOPYRANOSYLOXY-4',5-DIHYDROXYFLAVONE
4H-1-Benzopyran-4-one,7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)
4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-
7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 7- (.beta.-D-glucopyranosyloxy)-5-hydroxy-2-(4- hydroxyphenyl)-
4H-1-Benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)- (9ci)
所屬類別
生物化工：中草藥成分物理化學(xué)性質(zhì)
外觀性狀白色結(jié)晶體，可溶于甲醇、乙醇、DMSO等有機(jī)溶劑，來源于廣藿香、仙鶴草，蓰草，構(gòu)樹葉。
熔點(diǎn)230-237°C
沸點(diǎn)788.9±60.0 °C(Predicted)
密度1.642±0.06 g/cm3(Predicted)
儲(chǔ)存條件Inert atmosphere,2-8°C
溶解度DMSO（輕微，超聲處理），甲醇（輕微）
酸度系數(shù)(pKa)6.13±0.40(Predicted)
形態(tài)neat
顏色淡黃色至黃色
BRN65669
穩(wěn)定性吸濕性
InChIKeyKMOUJOKENFFTPU-YUVSVTSJNA-N
SMILESC1(C2=CC=C(O)C=C2)OC2=C(C(=CC(OC3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C2)O)C(=O)C=1 |&1:17,20,22,24,r|
LogP-0.040 (est)
CAS 數(shù)據(jù)庫578-74-5(CAS DataBase Reference)
芹甙元-7-葡萄糖苷價(jià)格(試劑級)
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2024/11/08 | HY-N0578 | 芹甙元-7-葡萄糖苷 Apigenin 7-glucoside | 578-74-5 | 5mg | 950元 |
| 2024/11/08 | HY-N0578 | 芹甙元-7-葡萄糖苷 Apigenin 7-glucoside | 578-74-5 | 10 mM * 1 mLin DMSO | 1045元 |
| 2024/11/08 | HY-N0578 | 芹甙元-7-葡萄糖苷 Apigenin 7-glucoside | 578-74-5 | 10mg | 1450元 |
常見問題列表
生物活性
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside)，ROS 清除劑，具有抗增殖，抗氧化活性。體外研究
Apigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucoside provoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucoside enhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells.
Apigenin 7-glucoside specifically induces the differentiation of CD34
+
cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner.