5636-92-0
5636-92-0 結(jié)構(gòu)式
基本信息
中文別名
哌氯定 英文別名
picloxydineN,N''-Bis[4-chlorophenylamino(imino)methyl]-1,4-piperazinebiscarbimide amide
1,4-Piperazinedicarboximidamide, N1,N4-bis[[(4-chlorophenyl)amino]iminomethyl]-
N,N''-Bis[[(4-chlorophenyl)amino](imino)methyl]-1,4-piperazinebiscarbimide amide
物理化學(xué)性質(zhì)
沸點561.7±60.0 °C(Predicted)
密度1.50±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)11?+-.0.20(Predicted)
形態(tài)Solid
顏色White to off-white
常見問題列表
生物活性
Picloxydine是抗細(xì)菌 (antibacterial) 和牙菌斑活性的雜環(huán)雙胍。靶點
Bacterial
體內(nèi)研究
0.4% Picloxydine produces a highly significant drop in the number of aerobic organisms. 0.4% Picloxydine is far more effective than 0.2% Picloxydine or chlorhexidine in reducing the total viable count of oral aerobic and anaerobic organisms. Picloxydine is also used in eye drops in the topical therapy of trachoma.