5593-20-4
中文名稱
倍他米松二丙酸酯
英文名稱
Betamethasone 17,21-dipropionate
CAS
5593-20-4
EINECS 編號
227-005-2
分子式
C28H37FO7
MDL 編號
MFCD00133140
分子量
504.59
MOL 文件
5593-20-4.mol
更新日期
2025/01/09 08:30:33
5593-20-4 結(jié)構(gòu)式
基本信息
中文別名
倍他米松二丙酸酯二丙酸倍他米松酯
倍他米松17,21-二丙酸酯
二丙酸倍他咪松
英文別名
1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 17,21-DIPROPIONATE9a-fluoro-16b-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate
9ALPHA-FLUORO-16BETA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 17,21-DIPROPIONATE
BETAMETHASONE 17,21-DI-PROPIONATE
BETAMETHASONE 17-ALPHA,21-DIPROPIONATE
BETAMETHASONE DIPROPIONATE
diproderm
diprolene
diprosis
diprosone
9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate)
Betanmethasone Dipronate
Pregna-1,4-Diene-3,20-Dione,9-Fluoro-11-Hydroxy-16-Methyl-17,21-Bis(1-Oxopropoxy)-,(11Beta,16Beta)-
(11-beta,16-beta)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate
Betamethasonediproprionate
9--Fluoro-16--methyl-11,17,21-trihydroxy-1,4-pregnadiene-3,20-dione17,21-dipropionate
BETANMETHASONE DIPROPIONATE
BETAMETHASONEDIPROPIONATE,MICRONIZEDPOWDER,USP
Diprophos
Maxivate
所屬類別
原料藥：腎上腺皮質(zhì)激素類藥物理化學(xué)性質(zhì)
外觀性狀白色或類白色晶體。
熔點(diǎn)178 °C
比旋光度D26 +65.7° (dioxane)
沸點(diǎn)603.2±55.0 °C(Predicted)
密度1.1481 (estimate)
折射率69 ° (C=1, Dioxane)
儲存條件2-8°C
溶解度Practically insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in ethanol (96 per cent).
酸度系數(shù)(pKa)12.87±0.70(Predicted)
形態(tài)neat
顏色白色至淡黃色
Merck1180
InChIKeyCIWBQSYVNNPZIQ-JCOVECCMSA-N
SMILESC([C@]1([C@H](C[C@@]2([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)OC(=O)CC)(=O)COC(=O)CC |&1:1,2,4,6,16,18,20,23,r|
CAS 數(shù)據(jù)庫5593-20-4(CAS DataBase Reference)
安全數(shù)據(jù)
警示詞危險
危險性描述H360FD-H373
安全說明S22-S24/25
WGK Germany2
RTECS號TU4058000
海關(guān)編碼29372290
毒性LD50 ipr-mus: 103 mg/kg NIIRDN 6,753,82
5593-20-4(安全特性,毒性,儲運(yùn))
儲運(yùn)特性
通風(fēng)低溫干燥; 與庫房食品原料分開存放毒性分級
高毒急性毒性
腹腔-小鼠 LD50:103 毫克/公斤; 皮下-小鼠 LD50: 78.1 毫克/公斤可燃性危險特性
可燃; 燃燒產(chǎn)生有毒氟化物煙霧類別
有毒物品滅火劑
干粉,泡沫,沙土,二氧化碳, 霧狀水倍他米松二丙酸酯價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | HY-13571 | 倍他米松二丙酸酯 Betamethasone dipropionate | 5593-20-4 | 250mg | 500元 |
| 2024/11/08 | HY-13571 | 倍他米松二丙酸酯 Betamethasone dipropionate | 5593-20-4 | 10mM * 1mLin DMSO | 550元 |
| 2024/11/08 | B3166 | 17,21-二丙酸倍他米松酯 Betamethasone 17,21-Dipropionate | 5593-20-4 | 1G | 395元 |
常見問題列表
生物活性
Betamethasone Dipropionate (SCH 11460) 是糖皮質(zhì)激素類固醇，具有抗炎和免疫抑制特性。靶點(diǎn)
| Target | Value |
|
Glucocorticoid receptor
() |
體內(nèi)研究
Betamethasone dipropionate is a super high potency corticosteroid used to treat inflammatory skin conditions such as dermatitis, eczema and psoriasis. It is a synthetic analog of the adrenal corticosteroids.