40592-88-9
中文名稱
TLR4-IN-C34
英文名稱
Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate
CAS
40592-88-9
分子式
C17H27NO9
分子量
389.398
MOL 文件
40592-88-9.mol
更新日期
2023/06/26 10:40:54
40592-88-9 結(jié)構(gòu)式
基本信息
中文別名
ISOPROPYL 2-(ACETYLAMINO)-2-DEOXY á-D-GLUCOPYRANOSIDE 3,4,6-TRIACETATE 英文別名
C34TLR4-C34
TLR4-IN-C34
2-Acetamidopyranoside
Isopropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranoside
ISOPROPYL 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSIDE 3,4,6-TRIACETATE
Isopropyl 2-(acetylamino)-2-deoxy á-D-glucopyranoside 3,4,6-triacetate
1-Methylethyl 2-(acetylamino)-2-deoxy-a-Dglucopyranoside 3,4,6-triacetate
1-Methylethyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate
Isopropyl 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranoside, Min. 98%
所屬類別
生物化工：抑制劑
常見問題列表
用途
TLR4-IN-C34是一類新的toll樣受體4 (TLR4)抑制劑，是潛在的抗炎藥物。生物活性
TLR4-IN-C34 是具有口服活性的 TLR4 抑制劑，可改善內(nèi)毒素血癥和壞死性小腸結(jié)腸炎模型的全身炎癥。體內(nèi)研究
TLR4-IN-C34 (C34, 1 mg/kg, orally daily) could attenuate NEC severity and demonstrates a marked preservation of the intestinal mucosa.
| Animal Model: | Experimental NEC induced in 7-8 day old mice. |
| Dosage: | 1 mg/kg. |
| Administration: | Orally every morning. |
| Result: | Attenuated intestinal inflammation. |