17910-09-7
17910-09-7 結(jié)構(gòu)式
基本信息
莪術(shù)呋喃烯
莪術(shù)烯莪術(shù)烯
莪術(shù)烯對(duì)照品
莪術(shù)烯標(biāo)準(zhǔn)品
莪術(shù)烯(黃色油狀液體)
CURZERENE 莪術(shù)烯
Neocurzerene
Isogermafuren
Isogermafurene
Isofuranogermacrene
Benzofuran, 6-ethenyl-4,5,6,7-tetrahydro-3,6-dimethyl-5-(1-methylethenyl)-, (5R,6R)-rel-
物理化學(xué)性質(zhì)
常見(jiàn)問(wèn)題列表
GSTA1
Curzerene (0-100 μM; 24-72 hours) indicates that cell inhibition increases in a dose- and time-dependent manner, IC 50 to SPC A1 cells at 24, 48, and 72 h was 403.8 μM, 154.8 μM, and 47.01 μM, respectively. Curzerene (0-100 μM; 48 hours) exhibits a higher percentage of apoptotic and necrotic cells than that of the control group in SPC-A1cells. Curzerene(0-100 μM; 48 hours) indicates that the percentage of cells arrested in the G2/M phase increased from 9.26% in the control group cells to 17.57% in the cells treated with the highest dose. Curzerene (6.25-100 μM; 48 hours) decreases the mRNA expression of GSTA1 in SPC A1 cells. Curzerene (6.25-100 μM; 48 hours) decreases the protein expression of GSTA1 in SPC A1 cells.
Cell Viability Assay
| Cell Line: | SPC-A1 cells |
| Concentration: | 0 μM, 6.25 μM, 12.5 μM, 25 μM, 50 μM, 100 μM |
| Incubation Time: | 24 hours, 48 hours, 72 hours |
| Result: | Inhibited growth of non-small cell lung cancer SPC A1 cells in vitro. |
Apoptosis Analysis
| Cell Line: | SPC-A1 cells |
| Concentration: | 0 μM, 6.25 μM, 12.5 μM, 25 μM, 50 μM, 100 μM |
| Incubation Time: | 48 hours |
| Result: | Induced apoptosis of the cells in a dose-dependent manner. |
Apoptosis Analysis
| Cell Line: | SPC-A1 cells |
| Concentration: | 0 μM, 6.25 μM, 12.5 μM, 25 μM, 50 μM, 100 μM |
| Incubation Time: | 48 hours |
| Result: | Induced G2/M cell cycle arrest of SPC A1 cells. |
RT-PCR
| Cell Line: | SPC-A1 cells |
| Concentration: | 6.25 μM, 25 μM, 100 μM |
| Incubation Time: | 48 hours |
| Result: | Decreased GSTA1 mRNA expression. |