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1335210-35-9

中文名稱 DOLUTEGRAVIR 中間體
英文名稱 (4R,12aS)-N-(2,4-Difluorobenzyl)-7-Methoxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxaMide
CAS 1335210-35-9
分子式 C21H21F2N3O5
分子量 433.41
MOL 文件 1335210-35-9.mol
更新日期 2024/12/22 16:37:52
1335210-35-9 結(jié)構(gòu)式 1335210-35-9 結(jié)構(gòu)式

基本信息

中文別名
多替拉韋雜質(zhì)7
鄰甲基度魯特韋
多特格韋N-3
O-甲基度魯特韋
(4R,12AS)-N-((2,4-二氟苯基)甲基)-3,4,6,8,12,12A-六氫-7-甲氧基-4-甲基-6,8-二氧代-2H-吡啶并(1',2':4,5)吡嗪并(2,1-B)(1,3)惡嗪-9
(4R,12AS)-N-((2,4-二氟苯基)甲基)-3,4,6,8,12,12A-六氫-7-甲氧基-4-甲基-6,8-二氧代-2H-吡啶并(1',2':4,5)吡嗪并(2,1-B)(1,3)噁嗪-9-甲酰胺
(4R,12AS)-N-[(2,4-二氟苯基)甲基]-3,4,6,8,12,12A-六氫-7-甲氧基-4-甲基-6,8-二氧代-2H-吡啶并[1',2':4,5]吡嗪并[2,1-B][1,3]惡嗪-9-甲酰胺
英文別名
BNKY001-DL03
O-Methyl Dolutegravir
Dolutegravir O-Methyl Imp
Doultegravir O methyl impurity
Dolutegravir O-Methyl Impurity
(4R,12aS)-N-(2,4-Difluorobenzyl)-7-Methoxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxaMide
(4R,12aS)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-car boxamide
(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-, (4R,12aS)-
Dolutegravir impurity 5/O-Methyl Dolutegravir/(4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-methoxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
所屬類別
醫(yī)藥中間體:原料藥中間體

物理化學(xué)性質(zhì)

沸點(diǎn)684.3±55.0 °C(Predicted)
密度1.45±0.1 g/cm3(Predicted)
儲存條件Sealed in dry,Room Temperature
酸度系數(shù)(pKa)10.70±0.40(Predicted)

安全數(shù)據(jù)

危險性符號(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險性描述H302-H315-H319-H335
海關(guān)編碼38220090
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