1177356-70-5
中文名稱
(+)-Blebbistatin
英文名稱
(+)-Blebbistatin
CAS
1177356-70-5
分子式
C18H16N2O2
分子量
292.33
MOL 文件
1177356-70-5.mol
更新日期
2024/08/06 14:59:09
1177356-70-5 結(jié)構(gòu)式
基本信息
中文別名
(+)-BLEBBISTATIN 英文別名
(+)Blebbistatin,(+) Blebbistatin(+)-Blebbistatin - CAS 1177356-70-5 - Calbiochem
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aR)-
物理化學(xué)性質(zhì)
沸點507.3±60.0 °C(Predicted)
密度1.31±0.1 g/cm3(Predicted)
儲存條件-20C
溶解度DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 12.5 mg/ml
酸度系數(shù)(pKa)11.15±0.20(Predicted)
形態(tài)黃色固體
應(yīng)用領(lǐng)域
用途1
Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. It blocks both blebbing and cytokinesis at 50-100μM. A negative control for the (S)-(-)-Blebblastatin. [a]D= +110 (c= 1.21 CHCl3) (-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-on e