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1057677-92-5

英文名稱 2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol
CAS 1057677-92-5
分子式 C27H29N5O
分子量 439.552
MOL 文件 1057677-92-5.mol
1057677-92-5 結(jié)構(gòu)式 1057677-92-5 結(jié)構(gòu)式

基本信息

英文別名
2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol

應(yīng)用領(lǐng)域

用途一
LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth.
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