| Identification | Back Directory | [Name]
2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol | [CAS]
1057677-92-5 | [Synonyms]
2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol | [Molecular Formula]
C27H29N5O | [MOL File]
1057677-92-5.mol | [Molecular Weight]
439.552 |
| Hazard Information | Back Directory | [Description]
LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth. |
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