104869-31-0
104869-31-0 結(jié)構(gòu)式
基本信息
英文別名
NF 023NF023 hexasodium
NF 023 hydrate
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA
8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt
8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT
8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate
8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt
物理化學(xué)性質(zhì)
儲存條件Desiccate at RT
溶解度H2O: >20 mg/mL
溶解度H2O: >20 mg/mL
形態(tài)crystalline
顏色white
水溶解性溶于水至100mM
NF 023價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2024/11/08 | HY-108676 | NF 023 NF023 hexasodium | 104869-31-0 | 5mg | 2800元 |
| 2024/11/08 | HY-108676 | NF 023 NF023 hexasodium | 104869-31-0 | 10mg | 4500元 |
常見問題列表
生物活性
NF023 hexasodium 是具有選擇性的、競爭性的 P2X1 受體拮抗劑，其對人 P2X1、P2X3、P2X2 和 P2X4 的 IC50 值分別為 0.21 μM、28.9 μM、> 50 μM 和> 100 μM。體外研究
NF023 is selective for recombinant Gi alpha-1 and recombinant Go alpha (EC
50
value of approximately 300 nM).
NF023 inhibits P2X1 receptors in a voltage-insensitive manner. NF023 (5 and 30 μM) causes a shift of the concentration-response curve to the right without affecting the maximal response to ATP (K
B
=1.190.2 μM).
體內(nèi)研究
NF023 (100 μmol/kg i.v.) antagonizes vasopressor responses to α,β-mATP but not to noradrenaline In pithed rats.