| Identification | Back Directory | [Name]
NF 023 | [CAS]
104869-31-0 | [Synonyms]
NF 023
NF 023 hydrate
NF023 hexasodium
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA
8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt
8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT
8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT
8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate
8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt | [Molecular Formula]
C33H20N4Na6O19S6 | [MDL Number]
MFCD01074985 | [MOL File]
104869-31-0.mol | [Molecular Weight]
1106.86 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at RT | [solubility ]
H2O: >20 mg/mL
| [form ]
crystalline
| [color ]
white
| [Water Solubility ]
Soluble to 100 mM in water |
| Hazard Information | Back Directory | [Uses]
NF 023 is a subtype selective, competitive and reversible P2X1 receptor antagonist. | [Biological Activity]
A subtype-selective, competitive and reversible P2X 1 receptor antagonist. Displays IC 50 values of 0.21, 28.9, > 50 and > 100 μ M for human P2X 1 , P2X 3 , P2X 2 , and P2X 4 -mediated responses respectively. Selective over adrenoceptors, histamine and P2Y receptors. Also selectively inhibits the α -subunit of G o/i (EC 50 ~? 300 nM). | [Biochem/physiol Actions]
NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes. | [storage]
Desiccate at RT |
|
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
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| Website: |
http://www.energy-chemical.com |
| Company Name: |
MedChemExpress
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021-58955995 |
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www.medchemexpress.com |
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