| Identification | More | [Name]
4-Chloro-1,2-diaminobenzene | [CAS]
95-83-0 | [Synonyms]
3,4-DIAMINOCHLOROBENZENE
4-CHLORO-1,2-DIAMINOBENZENE
4-CHLORO-1,2-PHENYLENEDIAMINE
4-CHLORO-BENZENE-1,2-DIAMINE
4-CHLORO-O-PHENYLENEDIAMINE
4-CHLORO-PHENYLENE-1,2-DIAMINE
TIMTEC-BB SBB008908
1,2-benzenediamine,-chloro-
1,2-Diamino-4-chlorobenzene
2-Amino-4-chloroaniline
3,4-Diamino-1-chlorobenzene
4-Chloro-1,2-benzenediamine
4-chloro-2-benzenediamine
4-chloro-o-phenylenediamin
4-Chloro-ortho-phenylenediamine
4-Cl-o-Pd
C.I. 76015
c.i.76015
ci76015
NCI-C03292 | [EINECS(EC#)]
202-456-8 | [Molecular Formula]
C6H7ClN2 | [MDL Number]
MFCD00011691 | [Molecular Weight]
142.59 | [MOL File]
95-83-0.mol |
| Chemical Properties | Back Directory | [Appearance]
4-Chloro-o-phenylenediamine is a brown crystalline powder or leaflets from water; freezing/melting
point 5 6773C; also reported in lit. @ 76C. Slightly
soluble in water. | [Melting point ]
70-73 °C(lit.) | [Boiling point ]
232.49°C (rough estimate) | [density ]
1.2124 (rough estimate) | [refractive index ]
1.4877 (estimate) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
3.52±0.10(Predicted) | [color ]
White to off-white | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents. | [Water Solubility ]
16 g/L (20 ºC) | [BRN ]
508472 | [InChIKey]
BXIXXXYDDJVHDL-UHFFFAOYSA-N | [CAS DataBase Reference]
95-83-0(CAS DataBase Reference) | [IARC]
2B (Vol. 27, Sup 7) 1987 | [NIST Chemistry Reference]
1,2-Benzenediamine, 4-chloro-(95-83-0) | [EPA Substance Registry System]
95-83-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves . | [RIDADR ]
2811 | [WGK Germany ]
3
| [RTECS ]
SS8850000
| [F ]
8 | [Hazard Note ]
Irritant | [TSCA ]
Yes | [HS Code ]
29215900 | [Safety Profile]
Confirmed carcinogen
with experimental carcinogenic and
neoplastigenic data. Human mutation data
reported. When heated to decomposition it
emits toxic fumes of Cland NOx. See also
AROMATIC AMINES. | [Hazardous Substances Data]
95-83-0(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Description]
4-Chloro-o-phenylene-diamine is a browncrystalline powder or leaflets from water; Freezing/Meltingpoint =67-70℃; also reported at 76℃ | [Chemical Properties]
4-Chloro-o-phenylenediamine is a brown crystalline powder or leaflets from water; freezing/melting point 67-73°C; also reported in lit. @ 76°C. Slightly soluble in water. soluble in benzene, very soluble in ethanol, ether. | [Uses]
4-Chloro-o-phenylenediamine can be used as an oxidation base for dye preparation, as a chemical intermediate to produce 5-chlorobenzotriazole, as a curing agent for epoxy resins, as a reagent in gas chromatography, and to synthesize experimental pharmaceuticals. It has been used as a chemical intermediate in dye production and was patented as a hair-dye component, but there is no evidence that it is currently used in the United States for these purposes (IARC 1982, HSDB 2009). | [Definition]
ChEBI: 4-Chloro-ortho-phenylenediamine is a member of monochlorobenzenes. Undergoes cyclizations and cyclocondensations to form benzimidazoles. | [Production Methods]
Commercial production of 4-chloro-o-PDA in the United
States was first reported in 1941. About 0.45–4.5 thousand kg
was produced by a U.S. company in 1977. It was also
produced by one company in the Federal Republic of
Germany. This compound has been patented as a hair dye
component, fur dyes, inks, and hair coloring formulations,
and is believed to be used to produce 5-chlorobenzotriazole,
an isomer of which is a photographic chemical.
The primary routes of potential human exposure to 4-
chloro-o-PDA are inhalation and dermal contact during its
production. Consumer exposure may occur from use of hair
dyes or products made from 5-chlorobenzotriazole. | [General Description]
4-chloro-o-phenylenediamine appears as brown crystalline solid or powder. (NTP, 1992) | [Air & Water Reactions]
4-Chloro-1,2-diaminobenzene may be sensitive to prolonged exposure to air and light. Insoluble in water. | [Reactivity Profile]
4-Chloro-1,2-diaminobenzene is incompatible with strong oxidizers. 4-Chloro-1,2-diaminobenzene reacts with alpha-ketoacids to form quinoxalones. | [Fire Hazard]
Flash point data for 4-Chloro-1,2-diaminobenzene are not available. 4-Chloro-1,2-diaminobenzene is probably combustible. | [Potential Exposure]
This organochlorine material has been
patented as a hair dye component. It is believed to be used
in production of photographic chemicals. In varying
degrees, organochlorines are absorbed from the gut and
also by the lung and across the skin. | [First aid]
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least20 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit | [Carcinogenicity]
4-Chloro-o-phenylenediamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity fromstudies in experimental animals. | [storage]
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045. Store in tightlyclosed containers in a cool, well-ventilated place or arefrigerator. | [Shipping]
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye
intermediates, solid, toxic, n.o.s., Hazard Class: 6.1;
Labels: 6.1-Poisonous materials, Technical Name Required. | [Purification Methods]
Recrystallise the diamine from pet. ether. [Beilstein 13 IV 68.] | [Incompatibilities]
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Light sensitive. It reacts
with alpha-ketoacids to form quinoxalones or
benzopyrazines. | [Waste Disposal]
Disposal of unused product
must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of appropriate
protective equipment. For proper handling and disposal,
always comply with federal, state, and local regulations. |
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