| Identification | More | [Name]
2,4-Dimethyl aniline | [CAS]
95-68-1 | [Synonyms]
1-AMINO-2,4-DIMETHYLBENZENE
2,4-DIMETHYLAMINOBENZENE
2,4-DIMETHYLANILINE
2,4-XYLIDINE
2-METHYL-P-TOLUIDINE
4-AMINO-1,3-DIMETHYLBENZENE
4-AMINO-3-METHYLTOLUENE
4-AMINO-M-XYLENE
4-METHYL-O-TOLUIDINE
AKOS BBS-00003656
ASYM-M-XYLIDINE
LABOTEST-BB LTBB000473
M-XYLIDINE
2,4-dimethyl-anilin
2,4-dimethyl-benzenamin
2,4-Dimethylbenzenamine
2,4-dimethyl-Benzenamine
2,4-Dimethylbenzeneamine
2,4-Dimethylphenylamine
2,4-Xylylamine | [EINECS(EC#)]
202-440-0 | [Molecular Formula]
C8H11N | [MDL Number]
MFCD00007738 | [Molecular Weight]
121.18 | [MOL File]
95-68-1.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless to yellow or dark brown liquid | [Melting point ]
16 °C | [Boiling point ]
218 °C(lit.)
| [density ]
0.98 g/mL at 25 °C(lit.)
| [vapor density ]
4.2 (vs air)
| [vapor pressure ]
0.16 mm Hg ( 25 °C)
| [refractive index ]
n20/D 1.558(lit.)
| [Fp ]
195 °F
| [storage temp. ]
room temp | [solubility ]
5g/l | [form ]
Liquid | [pka]
pK1:4.89(+1) (25°C) | [color ]
Clear yellow to red-brown | [Odor]
Amine like | [PH]
7 (22g/l, H2O, 20℃) | [Stability:]
Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides, chloroformates, halogens. | [explosive limit]
1.1-7.0%(V) | [Water Solubility ]
5 g/L (20 ºC) | [Merck ]
14,10084 | [BRN ]
636243 | [Dielectric constant]
4.9000000000000004 | [LogP]
2.02 at 23℃ and pH8 | [CAS DataBase Reference]
95-68-1(CAS DataBase Reference) | [IARC]
3 (Vol. 16, Sup 7) 1987 | [NIST Chemistry Reference]
Benzenamine, 2,4-dimethyl-(95-68-1) | [EPA Substance Registry System]
95-68-1(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R33:Danger of cumulative effects.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN 1711 6.1/PG 2
| [WGK Germany ]
2
| [RTECS ]
ZE8925000
| [F ]
8 | [Autoignition Temperature]
860 °F | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
II | [HS Code ]
29214910 | [Safety Profile]
Suspected carcinogen.
Poison by ingestion. Mutation data reported. When heated to decomposition it emits
toxic fumes of NOx. See also other xylidine
entries. | [Hazardous Substances Data]
95-68-1(Hazardous Substances Data) |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
m-Xylene-->4-Nitro-1,3-dimethylbenzene-->2,6-Dimethyl-1-nitrobenzene | [Preparation Products]
2,6-Dimethylaniline-->Amitraz-->AMITRAZ METABOLITE HYDROCHLORIDE-->SOLVENT YELLOW 85-->Solvent Yellow 18-->2,4-Dimethylbromobenzene-->1,4-DICYANONAPHTHALENE-->2,4-Dimethyl-3-nitroaniline-->4-CHLORO-M-XYLENE-->5,7-DIMETHYLISATIN-->2,4-DIMETHYL-5-NITROANILINE-->2,4-Dimethylphenylhydrazine hydrochloride-->Naphtho[2,1-d]thiazole-8-sulfonic acid, 2-(3-aminophenyl)-7-[(2,4-dimethylphenyl)azo]-6-hydroxy-, monosodium salt-->disodium 5-(acetylamino)-3-[(dimethylphenyl)azo]-4-hydroxynaphthalene-2,7-disulphonate-->2,4-bis(2,4-xylylazo)resorcinol-->Direct Red 264-->Jute Scarlet R |
| Hazard Information | Back Directory | [General Description]
Dark brown liquid. | [Reactivity Profile]
2,4-XYLIDINE(95-68-1) ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. | [Air & Water Reactions]
This chemical may be sensitive to prolonged exposure to air. Slightly soluble in water. | [Fire Hazard]
This chemical is combustible. | [Chemical Properties]
colourless to yellow or dark brown liquid | [Uses]
2,4-Xylidine, as part of the commercial mixture, has the same
uses as xylidine. | [Definition]
ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 4-positions are replaced by methyl groups. A clear to yellow liquid, it is used in production of certain dyes, pesticides and other chemicals. | [Metabolic pathway]
The major urinary metabolite of 2,4-dimethylaniline
(2,4-DMA) in rats is N-acetyl-4-amino-3-methylbenzoic
acid, while in dogs, it is 6-hydroxy-2,4-dimethylaniline.
Dogs also produce a smaller amount of unacetylated
4-amino-3-methylbenzoic acid and its glycine
conjugate. 2,6-Dimethylaniline (2,6-DMA) is
metabolized principally to 4-hydroxy-2,6-
dimethylaniline in both species, but dogs also produce
a significant quantity of 2-amino-3-methylbenzoic acid along with a trace amount of the glycine conjugate of
the latter metabolite and 2,6-dimethylnitrosobenzene.
Trace levels of an unknown postulated to be 3,5-
dimethyl-4-iminoquinone are found in dog urine. | [Purification Methods]
Convert uns-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry it over KOH and fractionally distil. The acetyl derivative has m 130o, the benzoyl derivative has m 192o, and the picrate has m 209o. [Beilstein 12 H 1111, 12 IV 2545.] |
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