| Identification | Back Directory | [Name]
NUCLEOSIDE PHOSPHORYLASE | [CAS]
9030-21-1 | [Synonyms]
PNP
C:C&B24
EC 2.4.2.1
Purine-nucleoside phosp
NUCLEOSIDE PHOSPHORYLASE
PURINE NUCLEOSIDE PHOSPHORYLASE
Phosphorylase, purine nucleoside
Deoxyribonucleoside phosphorylase
Purine ribonucleoside phosphorylase
PNP/Purine-nucleoside phosphorylase
NUCLEOSIDE PHOSPHORYLASE USP/EP/BP
Purine deoxynucleoside phosphorylase
Purine deoxyribonucleoside phosphorylase
NUCLEOSIDE PHOSPHORYLASE FROM HUMAN*BLOO D
Purine nucleoside phosphorylase, Recombinant
Native Microorganisms Nucleoside Phosphorylase
Purine Nucleoside Phosphorylase, ≥200U/mg protein
Purine nucleoside phosphorylase [ >=200 units/mg]
Nucleoside Phosphorylase from microorganisms
Native Bacillus sp. Purine Nucleoside Phosphorylase
Native Microorganism Purine-nucleoside phosphorylase
Nucleoside Phosphorylase from bacterial, Recombinant
PURINE NUCLEOSIDE: ORTHOPHOSPHATE RIBOSYLTRANSFERASE
Recombinant mutant (Met62Val) purine nucleoside phosphorylase from E. coli
Purine nucleoside phosphorylase, Purine nucleoside:orthophosphate ribosyltransferase
Nucleoside Phosphorylase bacterial,PNP, Purine nucleoside phosphorylase, Purine nucleoside:orthophosphate ribosyltransferase | [EINECS(EC#)]
232-857-3 | [Molecular Formula]
NULL | [MDL Number]
MFCD00131739 | [MOL File]
9030-21-1.mol | [Molecular Weight]
252.227 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [form ]
lyophilized powder
| [color ]
White to off-white | [InChI]
InChI=1/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/s3 | [InChIKey]
MRWXACSTFXYYMV-DOGWMMLDNA-N | [SMILES]
O1[C@@H](N2C3=C(N=C2)C=NC=N3)[C@H](O)[C@H](O)[C@H]1CO |&1:1,11,13,15,r| |
| Hazard Information | Back Directory | [Chemical Properties]
Powder | [Uses]
Nucleoside Phosphorylase from microorganisms has been used:
- in phosphopentomutase assay for adenosine synthesis
- for the conversion of 7-methylthioguanosine to 7-methylthioguanine
- in the synthesis of cytokinins in lyophilized cotton plant samples
| [General Description]
Nucleoside Phosphorylase are trimeric and have a molecular mass of about 100 kDa. Each monomer consists of a mixed β-sheet core flanked by eight α-helices and a purine binding in hydrophobic pocket. | [Biochem/physiol Actions]
Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine. Mutations in the PNP gene are responsible for purine nucleoside phosphorylase deficiency. |
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