Identification | Back Directory | [Name]
Hyaluronidase | [CAS]
37326-33-3 | [Synonyms]
Hydase Neopermease Hyalosidase ovinetestes EC 4.2.99.1 EC 3.2.1.35 EC: 3.2.1.35 EC: 3.1.2.35 IUB: 3.2.1.35 HYALURONIDASE Chondroitinase EC 3.2.1.35 TYPE V EC 3.2.1.35 TYPE II EC 3.2.1.35 TYPE I-S HYALURONIDASE TYPE V Hyaluronoglucosidase EC 3.2.1.35 TYPE IV-S EC 3.2.1.35 TYPE VIII EC 3.2.1.35 TYPE VI-S HYALURONIDASE TYPE II HYALURONIDASE TYPE III HYALURONIDASE TYPE I-S HYALURONIDASE TYPE IV-S HYALURONIDASE TYPE VIII HYALURONIDASE TYPE VI-S HYALURONOGLUCOSAMINIDASE HYALURONIDASE OVINE TESTES HYALURONIDASE BOVINE TESTES HYALURONATE GLYCANOHYDROLASE Hyaluronidase froMthe testes Hyaluronidasefrombovinetestes HYALURONATE 4-GLYCANOHYDROLASE HYALURONOGLUCOSAMINIDASE TYPE V Hyaluronidase from sheep testes HYALURONIDASE, SALT-FREE, BOVINE HYALURONOGLUCOSAMINIDASE TYPE II HYALURONOGLUCOSAMINIDASE TYPE III HYALURONOGLUCOSAMINIDASE TYPE I-S HYALURONOGLUCOSAMINIDASE TYPE IV-S HYALURONOGLUCOSAMINIDASE TYPE VIII HYALURONOGLUCOSAMINIDASE TYPE VI-S HyaluronidaseExLeech(E.C.3.2.1.3.6) HYALURONATE 4-GLYCANOHYDROLASE TYPE V HYALURONATE 4-GLYCANOHYDROLASE TYPE II HYALURONIDASE TYPE V FROM SHEEP TESTES HYALURONIDASE TYPE II FROM SHEEP TESTES HYALURONATE 4-GLYCANOHYDROLASE TYPE III HYALURONATE 4-GLYCANOHYDROLASE TYPE I-S HYALURONATE 4-GLYCANOHYDROLASE TYPE IV-S HYALURONATE 4-GLYCANOHYDROLASE TYPE VIII HYALURONATE 4-GLYCANOHYDROLASE TYPE VI-S Hyaluronidase from ovine testes, lyophil. HYALURONIDASE TYPE I-S FROM*BOVINE TESTE S HYALURONIDASE TYPE VIII*FROM BOVINE TEST ES HYALURONIDASE TYPE IV-S FROM*BOVINE TEST ES HYALURONIDASE FROM BOVINE TESTES, ~0.1 U /MG Hyaluronidase from ovine testes min. 1 000 U/mg Hyaluronidase (from bovine testes), lyophilized HYALURONIDASE TYPE IV-S FROM BOVINE*TEST ES EMBRYO T HYALURONIDASE FROM OVINE TESTES, LYOPH., ~0.25 U/MG HYALURONIDASE, STREPTOMYCES HYALURONLYTICUS NOV SPECIES Hyaluronidase froM ovine testes Min. 1 000 U/Mg lyophil. Hyaluronidase from bovine testes Vetec(TM) reagent grade Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase HYALURONIDASE FROM SHEEP TESTES, LYOPH., ST.-FR.,~0.02 U/MG* Hyaluronidase from bovine testes,Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase | [EINECS(EC#)]
253-464-3 | [Molecular Formula]
NULL | [MDL Number]
MFCD00131351 |
Chemical Properties | Back Directory | [Definition]
Any of a class of soluble enzymes produced in mammalian testes that catalyze cleavage of glycosidic
bonds of oartucular mucopolysaccharides. As a
component of venoms, it reduces the viscosity of
connective tissues and promotes tissue penetration
of the ve | [Appearance]
White or yellowish-white, amorphous powder. | [storage temp. ]
−20°C
| [solubility ]
Soluble in water, practically insoluble in acetone and in anhydrous ethanol | [form ]
powder
| [color ]
yellow-brown
| [Uses]
Used to promote absorption of fluid into tissues. |
Hazard Information | Back Directory | [Chemical Properties]
White or yellowish-white, amorphous powder. | [General Description]
Hyaluronidase is a hyaluronic acid-metabolizing enzyme. It is found in the venoms of snake, honeybee and hymenoptera. Hyaluronidase degrades hyaluronic acid (HA), which enhances membrane permeability, lowers viscosity and increases tissue permeability. It enhances the diffusion of local anesthetics, lowers the size of myocardial infarction, improves the effects of anticancer drugs and prevents perineal trauma during spontaneous delivery. | [Biochem/physiol Actions]
Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression. | [Purification Methods]
Hyaluronidase is purified by chromatography on DEAE-cellulose prior to use. [Distler & Jourdain J Biol Chem 248 6772 1973.] |
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