| Identification | Back Directory | [Name]
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid | [CAS]
890842-28-1 | [Synonyms]
CS-1142
GSK 650394
GSK650394 (Free base)
SGK inhibitor GS650394
2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl-benzoicacid
Benzoic acid, 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)- | [Molecular Formula]
C25H22N2O2 | [MDL Number]
MFCD12828779 | [MOL File]
890842-28-1.mol | [Molecular Weight]
382.45 |
| Hazard Information | Back Directory | [Uses]
GSK-650394 has been used as a serum and glucocorticoid-activated kinase (SGK1) inhibitor. | [Definition]
ChEBI: 2-cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid is a phenylpyridine. | [Biochem/physiol Actions]
GSK-650394 has an IC50 value of 62?nM for serum and glucocorticoid-activated kinase-1 (SGK1) and 103?nM for SGK2. It has an ability to stop viral replication at concentrations that are nontoxic to cells. | [storage]
Store at RT |
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