Identification | Back Directory | [Name]
3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro | [CAS]
878671-96-6 | [Synonyms]
2,3-Butanedione,4-bromo- 3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-napht... 3-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-5-thiol 3-amino-4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5-thione 3-Amino-4-(4-cyclopropyl-1-naphthyl)-1H-1,2,4-triazole-5(4H)-thione 3-Amino-4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione 3-amino-4 - (4-cyclopropylnaphthalene - 1-yl) -1H-1,2, 4-triazole-5-thione 3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-phthalenyl)-2,4-dihydro 5-amino-4-(4-cyclopropylnaphthalen-1-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro-3H-1,2,4-Triazole-3-thione 3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro 5-amino-4 -(4-cyclopropyl-1-naphthalene)-2, 4-dihydro-3H-1,2, 4-thiazole-3-mercaptan 3H-1,2,4-TRIAZOLE-3-THIONE,5-AMINO-4-(4-CYCLOPROPYL-1- NAPHTHALENYL)-2,4-DIHYDRO LESINURAD INTERMEDIATE | [Molecular Formula]
C15H14N4S | [MDL Number]
MFCD09991698 | [MOL File]
878671-96-6.mol | [Molecular Weight]
282.36 |
Chemical Properties | Back Directory | [Boiling point ]
475.2±38.0 °C(Predicted) | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
8.22±0.20(Predicted) |
Hazard Information | Back Directory | [Uses]
5-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol is a derivative of 5-Amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro-3H-1,2,4-Triazol-3-one (A602165), which is an impurity of the drug Lesinuard (L329700), which is used to synthesize febuxostat, a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. |
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