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ChemicalBook--->CAS DataBase List--->877399-00-3

877399-00-3

877399-00-3 Structure

877399-00-3 Structure
IdentificationBack Directory
[Name]

(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
[CAS]

877399-00-3
[Synonyms]

Crizotinib-H
Crizotinib Impurity 3
Crizotinib intermediates 1
Chiral intermediate of crizotinib
chiral intermediates of Crizotinib
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)etho
chiral intermediates of Crizotinib Company Standards
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin...
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
(R)-5-broMo-3-[1-(2,6-dichloro-3-fluoropehnyl)ethoxy]pyridin-2-aMine
5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy) yridine-2-amine
[5-Bromo-3-[(1R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine
2-PyridinaMine, 5-broMo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-
(R)-5-BroMo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylaMine
(R)-5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine
5-bromo-3-[(1 R)-(2,6-dichloro-3-fluorophenyl) ethoxy] pyridine-2-yl] amine
(R) -5-bromo-3 - (1- (2, 6-dichloro-3-fluorophenyl) ethoxy) pyridine-2-amine
[5-Bromo-3-[[(R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-2-yl]amine
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine ISO 9001:2015 REACH
InterMediate Ⅰof Crizotinib (R)-5-broMo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine
[EINECS(EC#)]

700-798-7
[Molecular Formula]

C13H10BrCl2FN2O
[MDL Number]

MFCD18207061
[MOL File]

877399-00-3.mol
[Molecular Weight]

380
Chemical PropertiesBack Directory
[Melting point ]

107.0 to 111.0 °C
[Boiling point ]

423.4±40.0 °C(Predicted)
[density ]

1.643
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[form ]

powder to crystal
[pka]

5.55±0.10(Predicted)
[color ]

White to Light yellow to Light orange
[InChI]

InChI=1S/C13H10BrCl2FN2O/c1-6(11-8(15)2-3-9(17)12(11)16)20-10-4-7(14)5-19-13(10)18/h2-6H,1H3,(H2,18,19)/t6-/m1/s1
[InChIKey]

URFUZAZEKBBCEY-ZCFIWIBFSA-N
[SMILES]

C1(N)=NC=C(Br)C=C1O[C@@H](C1=C(Cl)C=CC(F)=C1Cl)C
Safety DataBack Directory
[HS Code ]

2933.39.9200
Hazard InformationBack Directory
[Chemical Properties]

Pale yellow solid
[Uses]

(R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine is used in preparation of Crizotinib intermediate.
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